20210104-lab meeting_麗宇 | 賴亮全實驗室

索引

00:00 1.
index 1
00:16 2.
Introduction
00:19 3.
Keywords
00:30 4.
RNA categories
01:08 5.
Long non-coding RNA functions
01:59 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
02:49 7.
Slide 7
03:03 8.
Results
03:05 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
04:46 10.
Slide 10
05:17 11.
Malat1 suppresses the metastatic ability of breast cancer cells
06:30 12.
Slide 12
07:06 13.
MALAT1 interacts with TEAD-family members
09:24 14.
Conclusion
09:46 15.
Slide 15
09:57 16.
In vitro and In vivo
10:14 17.
Keywords
11:06 18.
Results
11:08 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
12:11 20.
Slide 20
13:37 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
14:21 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
14:49 23.
Slide 23
16:02 24.
Slide 24
16:58 25.
Slide 25
17:42 26.
Malat1 physically binds to Bim and E-selectin
18:05 27.
Conclusion
18:22 28.
Slide 28
18:52 29.
PI3K/PTEN/Akt pathway
20:26 30.
Results
20:27 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
20:51 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
21:19 33.
Slide 33
23:26 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
23:46 35.
Slide 35
25:31 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
26:37 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
26:58 38.
Slide 38
27:37 39.
Conclusion
28:21 40.
THANK YOU
28:33 41.
Slide 41
28:41 42.
** after 20210104_Lab meeting.pptx
28:57 43.
Slide 35
29:47 44.
Keywords
29:53 45.
Results
29:54 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
29:55 47.
Slide 20
29:55 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
29:56 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
29:57 50.
Slide 23
32:31 51.
Slide 24
32:32 52.
Slide 25
32:32 53.
Malat1 physically binds to Bim and E-selectin
32:33 54.
Conclusion
32:33 55.
Slide 28
32:34 56.
PI3K/PTEN/Akt pathway
32:34 57.
Results
32:34 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
32:37 59.
Long non-coding RNA functions
35:34 60.
RNA categories
35:45 61.
Long non-coding RNA functions
35:45 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
36:00 63.
Conclusion
36:41 64.
Slide 28
36:42 65.
PI3K/PTEN/Akt pathway
38:52 66.
Results
38:54 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
38:56 68.
Results
38:56 69.
PI3K/PTEN/Akt pathway
38:56 70.
Slide 28
38:57 71.
Conclusion
38:58 72.
Malat1 physically binds to Bim and E-selectin
38:58 73.
Slide 25
38:59 74.
Slide 24
39:00 75.
Slide 23
39:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
39:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
39:01 78.
Slide 20
39:01 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
39:02 80.
Results
39:02 81.
Keywords
39:03 82.
In vitro and In vivo
39:03 83.
Slide 15
39:04 84.
Conclusion
39:04 85.
MALAT1 interacts with TEAD-family members
39:04 86.
Slide 12
39:07 87.
Malat1 suppresses the metastatic ability of breast cancer cells
39:26 88.
Slide 10
39:27 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
39:55 90.
Results
39:56 91.
Slide 7
39:57 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
39:58 93.
Long non-coding RNA functions
39:58 94.
RNA categories
39:59 95.
Keywords
40:00 96.
Introduction
40:00 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
40:05 98.
** after 20210104_Lab meeting.pptx
41:22 99.
Slide 47
48:06 100.
Keywords
48:08 101.
In vitro and In vivo
48:08 102.
Slide 15
48:09 103.
Conclusion
48:09 104.
MALAT1 interacts with TEAD-family members
48:10 105.
Conclusion
49:10 106.
Slide 42
49:12 107.
Slide 41
49:12 108.
THANK YOU
49:13 109.
Conclusion
52:54 110.
THANK YOU
52:56 111.
Slide 41
52:59 112.
** after 20210104_Lab meeting.pptx

筆記 (0)

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討論

00:00 1.
index 1
00:16 2.
Introduction
00:19 3.
Keywords
00:30 4.
RNA categories
01:08 5.
Long non-coding RNA functions
01:59 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
02:49 7.
Slide 7
03:03 8.
Results
03:05 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
04:46 10.
Slide 10
05:17 11.
Malat1 suppresses the metastatic ability of breast cancer cells
06:30 12.
Slide 12
07:06 13.
MALAT1 interacts with TEAD-family members
09:24 14.
Conclusion
09:46 15.
Slide 15
09:57 16.
In vitro and In vivo
10:14 17.
Keywords
11:06 18.
Results
11:08 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
12:11 20.
Slide 20
13:37 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
14:21 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
14:49 23.
Slide 23
16:02 24.
Slide 24
16:58 25.
Slide 25
17:42 26.
Malat1 physically binds to Bim and E-selectin
18:05 27.
Conclusion
18:22 28.
Slide 28
18:52 29.
PI3K/PTEN/Akt pathway
20:26 30.
Results
20:27 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
20:51 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
21:19 33.
Slide 33
23:26 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
23:46 35.
Slide 35
25:31 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
26:37 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
26:58 38.
Slide 38
27:37 39.
Conclusion
28:21 40.
THANK YOU
28:33 41.
Slide 41
28:41 42.
** after 20210104_Lab meeting.pptx
28:57 43.
Slide 35
29:47 44.
Keywords
29:53 45.
Results
29:54 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
29:55 47.
Slide 20
29:55 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
29:56 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
29:57 50.
Slide 23
32:31 51.
Slide 24
32:32 52.
Slide 25
32:32 53.
Malat1 physically binds to Bim and E-selectin
32:33 54.
Conclusion
32:33 55.
Slide 28
32:34 56.
PI3K/PTEN/Akt pathway
32:34 57.
Results
32:34 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
32:37 59.
Long non-coding RNA functions
35:34 60.
RNA categories
35:45 61.
Long non-coding RNA functions
35:45 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
36:00 63.
Conclusion
36:41 64.
Slide 28
36:42 65.
PI3K/PTEN/Akt pathway
38:52 66.
Results
38:54 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
38:56 68.
Results
38:56 69.
PI3K/PTEN/Akt pathway
38:56 70.
Slide 28
38:57 71.
Conclusion
38:58 72.
Malat1 physically binds to Bim and E-selectin
38:58 73.
Slide 25
38:59 74.
Slide 24
39:00 75.
Slide 23
39:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
39:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
39:01 78.
Slide 20
39:01 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
39:02 80.
Results
39:02 81.
Keywords
39:03 82.
In vitro and In vivo
39:03 83.
Slide 15
39:04 84.
Conclusion
39:04 85.
MALAT1 interacts with TEAD-family members
39:04 86.
Slide 12
39:07 87.
Malat1 suppresses the metastatic ability of breast cancer cells
39:26 88.
Slide 10
39:27 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
39:55 90.
Results
39:56 91.
Slide 7
39:57 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
39:58 93.
Long non-coding RNA functions
39:58 94.
RNA categories
39:59 95.
Keywords
40:00 96.
Introduction
40:00 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
40:05 98.
** after 20210104_Lab meeting.pptx
41:22 99.
Slide 47
48:06 100.
Keywords
48:08 101.
In vitro and In vivo
48:08 102.
Slide 15
48:09 103.
Conclusion
48:09 104.
MALAT1 interacts with TEAD-family members
48:10 105.
Conclusion
49:10 106.
Slide 42
49:12 107.
Slide 41
49:12 108.
THANK YOU
49:13 109.
Conclusion
52:54 110.
THANK YOU
52:56 111.
Slide 41
52:59 112.
** after 20210104_Lab meeting.pptx

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索引
筆記
討論
全螢幕

20210104-lab meeting_麗宇

長度: 53:33, 瀏覽: 665, 最近修訂: 2021-01-11

00:00 1.
index 1
00:16 2.
Introduction
00:19 3.
Keywords
00:30 4.
RNA categories
01:08 5.
Long non-coding RNA functions
01:59 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
02:49 7.
Slide 7
03:03 8.
Results
03:05 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
04:46 10.
Slide 10
05:17 11.
Malat1 suppresses the metastatic ability of breast cancer cells
06:30 12.
Slide 12
07:06 13.
MALAT1 interacts with TEAD-family members
09:24 14.
Conclusion
09:46 15.
Slide 15
09:57 16.
In vitro and In vivo
10:14 17.
Keywords
11:06 18.
Results
11:08 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
12:11 20.
Slide 20
13:37 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
14:21 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
14:49 23.
Slide 23
16:02 24.
Slide 24
16:58 25.
Slide 25
17:42 26.
Malat1 physically binds to Bim and E-selectin
18:05 27.
Conclusion
18:22 28.
Slide 28
18:52 29.
PI3K/PTEN/Akt pathway
20:26 30.
Results
20:27 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
20:51 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
21:19 33.
Slide 33
23:26 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
23:46 35.
Slide 35
25:31 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
26:37 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
26:58 38.
Slide 38
27:37 39.
Conclusion
28:21 40.
THANK YOU
28:33 41.
Slide 41
28:41 42.
** after 20210104_Lab meeting.pptx
28:57 43.
Slide 35
29:47 44.
Keywords
29:53 45.
Results
29:54 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
29:55 47.
Slide 20
29:55 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
29:56 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
29:57 50.
Slide 23
32:31 51.
Slide 24
32:32 52.
Slide 25
32:32 53.
Malat1 physically binds to Bim and E-selectin
32:33 54.
Conclusion
32:33 55.
Slide 28
32:34 56.
PI3K/PTEN/Akt pathway
32:34 57.
Results
32:34 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
32:37 59.
Long non-coding RNA functions
35:34 60.
RNA categories
35:45 61.
Long non-coding RNA functions
35:45 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
36:00 63.
Conclusion
36:41 64.
Slide 28
36:42 65.
PI3K/PTEN/Akt pathway
38:52 66.
Results
38:54 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
38:56 68.
Results
38:56 69.
PI3K/PTEN/Akt pathway
38:56 70.
Slide 28
38:57 71.
Conclusion
38:58 72.
Malat1 physically binds to Bim and E-selectin
38:58 73.
Slide 25
38:59 74.
Slide 24
39:00 75.
Slide 23
39:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
39:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
39:01 78.
Slide 20
39:01 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
39:02 80.
Results
39:02 81.
Keywords
39:03 82.
In vitro and In vivo
39:03 83.
Slide 15
39:04 84.
Conclusion
39:04 85.
MALAT1 interacts with TEAD-family members
39:04 86.
Slide 12
39:07 87.
Malat1 suppresses the metastatic ability of breast cancer cells
39:26 88.
Slide 10
39:27 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
39:55 90.
Results
39:56 91.
Slide 7
39:57 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
39:58 93.
Long non-coding RNA functions
39:58 94.
RNA categories
39:59 95.
Keywords
40:00 96.
Introduction
40:00 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
40:05 98.
** after 20210104_Lab meeting.pptx
41:22 99.
Slide 47
48:06 100.
Keywords
48:08 101.
In vitro and In vivo
48:08 102.
Slide 15
48:09 103.
Conclusion
48:09 104.
MALAT1 interacts with TEAD-family members
48:10 105.
Conclusion
49:10 106.
Slide 42
49:12 107.
Slide 41
49:12 108.
THANK YOU
49:13 109.
Conclusion
52:54 110.
THANK YOU
52:56 111.
Slide 41
52:59 112.
** after 20210104_Lab meeting.pptx

位置

資料夾名稱

2021

發表人

陳逸安

單位

賴亮全教授

建立

2021-01-11 10:50:37

最近修訂

2021-01-11 11:42:30

長度

53:33