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00:16
1.
index 1
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00:02
2.
Introduction
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00:11
3.
Keywords
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00:37
4.
RNA categories
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00:50
5.
Long non-coding RNA functions
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00:50
6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
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00:14
7.
Slide 7
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00:01
8.
Results
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01:40
9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
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00:31
10.
Slide 10
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01:12
11.
Malat1 suppresses the metastatic ability of breast cancer cells
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00:36
12.
Slide 12
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02:17
13.
MALAT1 interacts with TEAD-family members
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00:21
14.
Conclusion
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00:11
15.
Slide 15
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00:16
16.
In vitro and In vivo
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00:52
17.
Keywords
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00:02
18.
Results
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01:02
19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
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01:26
20.
Slide 20
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00:44
21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
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00:28
22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
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01:12
23.
Slide 23
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00:56
24.
Slide 24
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00:44
25.
Slide 25
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00:22
26.
Malat1 physically binds to Bim and E-selectin
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00:17
27.
Conclusion
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00:29
28.
Slide 28
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01:33
29.
PI3K/PTEN/Akt pathway
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00:00
30.
Results
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00:24
31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
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00:28
32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
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02:06
33.
Slide 33
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00:19
34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
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01:44
35.
Slide 35
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01:06
36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
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00:20
37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
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00:38
38.
Slide 38
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00:44
39.
Conclusion
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00:11
40.
THANK YOU
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00:08
41.
Slide 41
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00:15
42.
** after 20210104_Lab meeting.pptx
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00:49
43.
Slide 35
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00:06
44.
Keywords
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00:00
45.
Results
-
00:00
46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
-
00:00
47.
Slide 20
-
00:00
48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
-
00:00
49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
-
02:34
50.
Slide 23
-
00:00
51.
Slide 24
-
00:00
52.
Slide 25
-
00:00
53.
Malat1 physically binds to Bim and E-selectin
-
00:00
54.
Conclusion
-
00:00
55.
Slide 28
-
00:00
56.
PI3K/PTEN/Akt pathway
-
00:00
57.
Results
-
00:02
58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
-
02:57
59.
Long non-coding RNA functions
-
00:10
60.
RNA categories
-
00:00
61.
Long non-coding RNA functions
-
00:14
62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
-
00:40
63.
Conclusion
-
00:01
64.
Slide 28
-
02:10
65.
PI3K/PTEN/Akt pathway
-
00:01
66.
Results
-
00:02
67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
-
00:00
68.
Results
-
00:00
69.
PI3K/PTEN/Akt pathway
-
00:00
70.
Slide 28
-
00:00
71.
Conclusion
-
00:00
72.
Malat1 physically binds to Bim and E-selectin
-
00:00
73.
Slide 25
-
00:00
74.
Slide 24
-
00:00
75.
Slide 23
-
00:00
76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
-
00:00
77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
-
00:00
78.
Slide 20
-
00:00
79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
-
00:00
80.
Results
-
00:00
81.
Keywords
-
00:00
82.
In vitro and In vivo
-
00:00
83.
Slide 15
-
00:00
84.
Conclusion
-
00:00
85.
MALAT1 interacts with TEAD-family members
-
00:02
86.
Slide 12
-
00:18
87.
Malat1 suppresses the metastatic ability of breast cancer cells
-
00:01
88.
Slide 10
-
00:28
89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
-
00:00
90.
Results
-
00:00
91.
Slide 7
-
00:00
92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
-
00:00
93.
Long non-coding RNA functions
-
00:01
94.
RNA categories
-
00:00
95.
Keywords
-
00:00
96.
Introduction
-
00:04
97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
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01:16
98.
** after 20210104_Lab meeting.pptx
-
06:44
99.
Slide 47
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00:01
100.
Keywords
-
00:00
101.
In vitro and In vivo
-
00:00
102.
Slide 15
-
00:00
103.
Conclusion
-
00:01
104.
MALAT1 interacts with TEAD-family members
-
00:59
105.
Conclusion
-
00:01
106.
Slide 42
-
00:00
107.
Slide 41
-
00:00
108.
THANK YOU
-
03:41
109.
Conclusion
-
00:01
110.
THANK YOU
-
00:03
111.
Slide 41
-
00:33
112.
** after 20210104_Lab meeting.pptx