20210104-lab meeting_麗宇 | 賴亮全實驗室

Index

00:16 1.
index 1
00:02 2.
Introduction
00:11 3.
Keywords
00:37 4.
RNA categories
00:50 5.
Long non-coding RNA functions
00:50 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:14 7.
Slide 7
00:01 8.
Results
01:40 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:31 10.
Slide 10
01:12 11.
Malat1 suppresses the metastatic ability of breast cancer cells
00:36 12.
Slide 12
02:17 13.
MALAT1 interacts with TEAD-family members
00:21 14.
Conclusion
00:11 15.
Slide 15
00:16 16.
In vitro and In vivo
00:52 17.
Keywords
00:02 18.
Results
01:02 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
01:26 20.
Slide 20
00:44 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:28 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
01:12 23.
Slide 23
00:56 24.
Slide 24
00:44 25.
Slide 25
00:22 26.
Malat1 physically binds to Bim and E-selectin
00:17 27.
Conclusion
00:29 28.
Slide 28
01:33 29.
PI3K/PTEN/Akt pathway
00:00 30.
Results
00:24 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:28 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
02:06 33.
Slide 33
00:19 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
01:44 35.
Slide 35
01:06 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
00:20 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
00:38 38.
Slide 38
00:44 39.
Conclusion
00:11 40.
THANK YOU
00:08 41.
Slide 41
00:15 42.
** after 20210104_Lab meeting.pptx
00:49 43.
Slide 35
00:06 44.
Keywords
00:00 45.
Results
00:00 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 47.
Slide 20
00:00 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
02:34 50.
Slide 23
00:00 51.
Slide 24
00:00 52.
Slide 25
00:00 53.
Malat1 physically binds to Bim and E-selectin
00:00 54.
Conclusion
00:00 55.
Slide 28
00:00 56.
PI3K/PTEN/Akt pathway
00:00 57.
Results
00:02 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
02:57 59.
Long non-coding RNA functions
00:10 60.
RNA categories
00:00 61.
Long non-coding RNA functions
00:14 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:40 63.
Conclusion
00:01 64.
Slide 28
02:10 65.
PI3K/PTEN/Akt pathway
00:01 66.
Results
00:02 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:00 68.
Results
00:00 69.
PI3K/PTEN/Akt pathway
00:00 70.
Slide 28
00:00 71.
Conclusion
00:00 72.
Malat1 physically binds to Bim and E-selectin
00:00 73.
Slide 25
00:00 74.
Slide 24
00:00 75.
Slide 23
00:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
00:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 78.
Slide 20
00:00 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 80.
Results
00:00 81.
Keywords
00:00 82.
In vitro and In vivo
00:00 83.
Slide 15
00:00 84.
Conclusion
00:00 85.
MALAT1 interacts with TEAD-family members
00:02 86.
Slide 12
00:18 87.
Malat1 suppresses the metastatic ability of breast cancer cells
00:01 88.
Slide 10
00:28 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:00 90.
Results
00:00 91.
Slide 7
00:00 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:00 93.
Long non-coding RNA functions
00:01 94.
RNA categories
00:00 95.
Keywords
00:00 96.
Introduction
00:04 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
01:16 98.
** after 20210104_Lab meeting.pptx
06:44 99.
Slide 47
00:01 100.
Keywords
00:00 101.
In vitro and In vivo
00:00 102.
Slide 15
00:00 103.
Conclusion
00:01 104.
MALAT1 interacts with TEAD-family members
00:59 105.
Conclusion
00:01 106.
Slide 42
00:00 107.
Slide 41
00:00 108.
THANK YOU
03:41 109.
Conclusion
00:01 110.
THANK YOU
00:03 111.
Slide 41
00:33 112.
** after 20210104_Lab meeting.pptx

Notes (0)

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Comment

00:16 1.
index 1
00:02 2.
Introduction
00:11 3.
Keywords
00:37 4.
RNA categories
00:50 5.
Long non-coding RNA functions
00:50 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:14 7.
Slide 7
00:01 8.
Results
01:40 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:31 10.
Slide 10
01:12 11.
Malat1 suppresses the metastatic ability of breast cancer cells
00:36 12.
Slide 12
02:17 13.
MALAT1 interacts with TEAD-family members
00:21 14.
Conclusion
00:11 15.
Slide 15
00:16 16.
In vitro and In vivo
00:52 17.
Keywords
00:02 18.
Results
01:02 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
01:26 20.
Slide 20
00:44 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:28 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
01:12 23.
Slide 23
00:56 24.
Slide 24
00:44 25.
Slide 25
00:22 26.
Malat1 physically binds to Bim and E-selectin
00:17 27.
Conclusion
00:29 28.
Slide 28
01:33 29.
PI3K/PTEN/Akt pathway
00:00 30.
Results
00:24 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:28 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
02:06 33.
Slide 33
00:19 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
01:44 35.
Slide 35
01:06 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
00:20 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
00:38 38.
Slide 38
00:44 39.
Conclusion
00:11 40.
THANK YOU
00:08 41.
Slide 41
00:15 42.
** after 20210104_Lab meeting.pptx
00:49 43.
Slide 35
00:06 44.
Keywords
00:00 45.
Results
00:00 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 47.
Slide 20
00:00 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
02:34 50.
Slide 23
00:00 51.
Slide 24
00:00 52.
Slide 25
00:00 53.
Malat1 physically binds to Bim and E-selectin
00:00 54.
Conclusion
00:00 55.
Slide 28
00:00 56.
PI3K/PTEN/Akt pathway
00:00 57.
Results
00:02 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
02:57 59.
Long non-coding RNA functions
00:10 60.
RNA categories
00:00 61.
Long non-coding RNA functions
00:14 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:40 63.
Conclusion
00:01 64.
Slide 28
02:10 65.
PI3K/PTEN/Akt pathway
00:01 66.
Results
00:02 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:00 68.
Results
00:00 69.
PI3K/PTEN/Akt pathway
00:00 70.
Slide 28
00:00 71.
Conclusion
00:00 72.
Malat1 physically binds to Bim and E-selectin
00:00 73.
Slide 25
00:00 74.
Slide 24
00:00 75.
Slide 23
00:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
00:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 78.
Slide 20
00:00 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 80.
Results
00:00 81.
Keywords
00:00 82.
In vitro and In vivo
00:00 83.
Slide 15
00:00 84.
Conclusion
00:00 85.
MALAT1 interacts with TEAD-family members
00:02 86.
Slide 12
00:18 87.
Malat1 suppresses the metastatic ability of breast cancer cells
00:01 88.
Slide 10
00:28 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:00 90.
Results
00:00 91.
Slide 7
00:00 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:00 93.
Long non-coding RNA functions
00:01 94.
RNA categories
00:00 95.
Keywords
00:00 96.
Introduction
00:04 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
01:16 98.
** after 20210104_Lab meeting.pptx
06:44 99.
Slide 47
00:01 100.
Keywords
00:00 101.
In vitro and In vivo
00:00 102.
Slide 15
00:00 103.
Conclusion
00:01 104.
MALAT1 interacts with TEAD-family members
00:59 105.
Conclusion
00:01 106.
Slide 42
00:00 107.
Slide 41
00:00 108.
THANK YOU
03:41 109.
Conclusion
00:01 110.
THANK YOU
00:03 111.
Slide 41
00:33 112.
** after 20210104_Lab meeting.pptx

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20210104-lab meeting_麗宇

Duration: 53:33, Browse: 392, Last Updated: 2021-01-11

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00:16 1.
index 1
00:02 2.
Introduction
00:11 3.
Keywords
00:37 4.
RNA categories
00:50 5.
Long non-coding RNA functions
00:50 6.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:14 7.
Slide 7
00:01 8.
Results
01:40 9.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:31 10.
Slide 10
01:12 11.
Malat1 suppresses the metastatic ability of breast cancer cells
00:36 12.
Slide 12
02:17 13.
MALAT1 interacts with TEAD-family members
00:21 14.
Conclusion
00:11 15.
Slide 15
00:16 16.
In vitro and In vivo
00:52 17.
Keywords
00:02 18.
Results
01:02 19.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
01:26 20.
Slide 20
00:44 21.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:28 22.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
01:12 23.
Slide 23
00:56 24.
Slide 24
00:44 25.
Slide 25
00:22 26.
Malat1 physically binds to Bim and E-selectin
00:17 27.
Conclusion
00:29 28.
Slide 28
01:33 29.
PI3K/PTEN/Akt pathway
00:00 30.
Results
00:24 31.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:28 32.
MALAT1 functioned as a ceRNA of miR-320 to regulate Pten in mouse cardiomyocytes
02:06 33.
Slide 33
00:19 34.
MALAT1 overexpression promoted myocardial apoptosis via miR-320/Pten axis
01:44 35.
Slide 35
01:06 36.
MALAT1 inhibition improved myocardial function through upregulating miR-320 in vivo
00:20 37.
MALAT1 knockdown alleviated myocardial injury and apoptosis by sponging miR-320 in vivo
00:38 38.
Slide 38
00:44 39.
Conclusion
00:11 40.
THANK YOU
00:08 41.
Slide 41
00:15 42.
** after 20210104_Lab meeting.pptx
00:49 43.
Slide 35
00:06 44.
Keywords
00:00 45.
Results
00:00 46.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 47.
Slide 20
00:00 48.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 49.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
02:34 50.
Slide 23
00:00 51.
Slide 24
00:00 52.
Slide 25
00:00 53.
Malat1 physically binds to Bim and E-selectin
00:00 54.
Conclusion
00:00 55.
Slide 28
00:00 56.
PI3K/PTEN/Akt pathway
00:00 57.
Results
00:02 58.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
02:57 59.
Long non-coding RNA functions
00:10 60.
RNA categories
00:00 61.
Long non-coding RNA functions
00:14 62.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:40 63.
Conclusion
00:01 64.
Slide 28
02:10 65.
PI3K/PTEN/Akt pathway
00:01 66.
Results
00:02 67.
MALAT1 and Pten were upregulated while miR-320 was suppressed in a mouse model of MI
00:00 68.
Results
00:00 69.
PI3K/PTEN/Akt pathway
00:00 70.
Slide 28
00:00 71.
Conclusion
00:00 72.
Malat1 physically binds to Bim and E-selectin
00:00 73.
Slide 25
00:00 74.
Slide 24
00:00 75.
Slide 23
00:00 76.
Inhibitory recovery of sensorimotor functions in Malat1 KO mice after focal cerebral ischemia.
00:00 77.
Genetic deficiency of Malat1 potentiates ischemic brain injury in mice
00:00 78.
Slide 20
00:00 79.
Induction of Malat1 levels in cultured BMECs after OGD and mouse cerebral microvessels after focal cerebral ischemia
00:00 80.
Results
00:00 81.
Keywords
00:00 82.
In vitro and In vivo
00:00 83.
Slide 15
00:00 84.
Conclusion
00:00 85.
MALAT1 interacts with TEAD-family members
00:02 86.
Slide 12
00:18 87.
Malat1 suppresses the metastatic ability of breast cancer cells
00:01 88.
Slide 10
00:28 89.
Targeted inactivation and restoration of Malat1 in mice suggest that Malat1 is a suppressor of breast cancer lung metastasis
00:00 90.
Results
00:00 91.
Slide 7
00:00 92.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
00:00 93.
Long non-coding RNA functions
00:01 94.
RNA categories
00:00 95.
Keywords
00:00 96.
Introduction
00:04 97.
Diverse roles of Long noncoding RNA MALAT1 in several pathologies
01:16 98.
** after 20210104_Lab meeting.pptx
06:44 99.
Slide 47
00:01 100.
Keywords
00:00 101.
In vitro and In vivo
00:00 102.
Slide 15
00:00 103.
Conclusion
00:01 104.
MALAT1 interacts with TEAD-family members
00:59 105.
Conclusion
00:01 106.
Slide 42
00:00 107.
Slide 41
00:00 108.
THANK YOU
03:41 109.
Conclusion
00:01 110.
THANK YOU
00:03 111.
Slide 41
00:33 112.
** after 20210104_Lab meeting.pptx

Location

Folder name

2021

Author

陳逸安

Branch

賴亮全教授

Created

2021-01-11 10:50:37

Last Updated

2021-01-11 11:42:30

Browse

392

Duration

53:33