• 00:22 1.
    index 1
  • 00:21 2.
    Gastric cancer (GC)
  • 00:22 3.
    Gastric cancer (GC)
  • 00:14 4.
    Human Genome
  • 00:22 5.
    Circular RNA (CircRNA)
  • 00:30 6.
    Biogenesis of circRNA
  • 00:35 7.
    CircRNA circularization - Alu element
  • 00:27 8.
    CircRNA circularization – RNA Binding Protein (RBP)
  • 00:33 9.
    Functions of circRNA
  • 00:20 10.
    The role of circRNAs in cancer
  • 00:58 11.
    Results
  • 00:38 12.
    Results
  • 00:16 13.
    Aim
  • 00:32 14.
    Results
  • 00:47 15.
    CircPDIA4 promoted migration and metastasis capabilities of gastric cancer cells in vitro and in vivo
  • 00:56 16.
    CircPDIA4 promoted migration and metastasis capabilities of gastric cancer cells in vitro and in vivo
  • 00:15 17.
    Summary
  • 00:07 18.
    Slide 18
  • 00:42 19.
    The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
  • 00:20 20.
    The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
  • 00:23 21.
    The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
  • 00:29 22.
    The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
  • 00:23 23.
    Summary
  • 00:05 24.
    Slide 24
  • 01:14 25.
    CircPDIA4 bound with DHX9 and ERK1/2
  • 01:08 26.
    CircPDIA4 sustained high phosphorylation levels of ERK1/2
  • 00:59 27.
    CircPDIA4 sustained high phosphorylation levels of ERK1/2 through interrupting binding of DUSP6 with ERK1/2
  • 00:29 28.
    CircPDIA4 sustained high phosphorylation levels of ERK1/2 through interrupting binding of DUSP6 with ERK1/2
  • 00:31 29.
    CircPDIA4 sustained high phosphorylation levels of ERK1/2 and reduced the sensitivity of ERKi
  • 00:00 30.
    Summary
  • 00:01 31.
    CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
  • 00:22 32.
    Summary
  • 01:03 33.
    CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
  • 00:41 34.
    CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
  • 00:46 35.
    CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
  • 00:35 36.
    CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
  • 00:26 37.
    Summary
  • 00:19 38.
    Conclusion
  • 00:14 39.
    Conclusion
  • 00:15 40.
    Conclusion
  • 00:24 41.
    Pros :
  • 00:02 42.
    Slide 40
  • 00:01 43.
    Slide 41
  • 26:11 44.
    ** after 20230307 seminar - 複本.pptx
  • Index
  • Notes
  • Comment
  • Fullscreen
20230213 lab meeting_怡君 (no sound)
Duration: 46:59, Browse: 78, Last Updated: 2023-05-16
    • 00:22 1.
      index 1
    • 00:21 2.
      Gastric cancer (GC)
    • 00:22 3.
      Gastric cancer (GC)
    • 00:14 4.
      Human Genome
    • 00:22 5.
      Circular RNA (CircRNA)
    • 00:30 6.
      Biogenesis of circRNA
    • 00:35 7.
      CircRNA circularization - Alu element
    • 00:27 8.
      CircRNA circularization – RNA Binding Protein (RBP)
    • 00:33 9.
      Functions of circRNA
    • 00:20 10.
      The role of circRNAs in cancer
    • 00:58 11.
      Results
    • 00:38 12.
      Results
    • 00:16 13.
      Aim
    • 00:32 14.
      Results
    • 00:47 15.
      CircPDIA4 promoted migration and metastasis capabilities of gastric cancer cells in vitro and in vivo
    • 00:56 16.
      CircPDIA4 promoted migration and metastasis capabilities of gastric cancer cells in vitro and in vivo
    • 00:15 17.
      Summary
    • 00:07 18.
      Slide 18
    • 00:42 19.
      The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
    • 00:20 20.
      The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
    • 00:23 21.
      The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
    • 00:29 22.
      The RBP QKI induced the formation of circPDIA4 in gastric cancer cells
    • 00:23 23.
      Summary
    • 00:05 24.
      Slide 24
    • 01:14 25.
      CircPDIA4 bound with DHX9 and ERK1/2
    • 01:08 26.
      CircPDIA4 sustained high phosphorylation levels of ERK1/2
    • 00:59 27.
      CircPDIA4 sustained high phosphorylation levels of ERK1/2 through interrupting binding of DUSP6 with ERK1/2
    • 00:29 28.
      CircPDIA4 sustained high phosphorylation levels of ERK1/2 through interrupting binding of DUSP6 with ERK1/2
    • 00:31 29.
      CircPDIA4 sustained high phosphorylation levels of ERK1/2 and reduced the sensitivity of ERKi
    • 00:00 30.
      Summary
    • 00:01 31.
      CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
    • 00:22 32.
      Summary
    • 01:03 33.
      CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
    • 00:41 34.
      CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
    • 00:46 35.
      CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
    • 00:35 36.
      CircPDIA4 competitively combined with DHX9 as a decoy to promote oncogenic circRNAs formation
    • 00:26 37.
      Summary
    • 00:19 38.
      Conclusion
    • 00:14 39.
      Conclusion
    • 00:15 40.
      Conclusion
    • 00:24 41.
      Pros :
    • 00:02 42.
      Slide 40
    • 00:01 43.
      Slide 41
    • 26:11 44.
      ** after 20230307 seminar - 複本.pptx
    Location
    Folder name
    2023
    Author
    黃照穎
    Branch
    賴亮全教授
    Created
    2023-02-13 10:01:13
    Last Updated
    2023-05-16 16:29:24
    Browse
    78
    Duration
    46:59