• 00:00 1.
    index 1
  • 00:24 2.
    Pancreatic cancer (PC)
  • 00:40 3.
    Hypoxia
  • 00:48 4.
    Pancreatic cancer (PC)
  • 00:49 5.
    Hypoxia
  • 01:18 6.
    Hypoxia-inducible factor 1-α (HIF-1a)
  • 01:19 7.
    Hypoxia
  • 02:12 8.
    Hypoxia-inducible factor 1-α (HIF-1a)
  • 02:18 9.
    Circular RNA (circRNA)
  • 02:19 10.
    Hypoxia-inducible factor 1-α (HIF-1a)
  • 02:26 11.
    Circular RNA (circRNA)
  • 02:26 12.
    Hypoxia-inducible factor 1-α (HIF-1a)
  • 02:27 13.
    Hypoxia
  • 02:27 14.
    Hypoxia-inducible factor 1-α (HIF-1a)
  • 03:34 15.
    Circular RNA (circRNA)
  • 06:13 16.
    Circular RNA (circRNA)
  • 06:33 17.
    Functions of circRNA
  • 07:46 18.
    MicroRNA (miRNA)
  • 11:54 19.
    Interplay between circRNA and miRNA
  • 13:46 20.
    Exosome
  • 14:16 21.
    Exosomal circRNA
  • 14:30 22.
    Exosomal circRNA
  • 14:42 23.
    Exosomal circRNA
  • 14:54 24.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 14:57 25.
    Exosomal circRNA
  • 15:02 26.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 21:28 27.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 24:17 28.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 24:18 29.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 29:08 30.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 35:40 31.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 42:15 32.
    Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
  • 45:14 33.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 47:08 34.
    ** after 20230703 lab meeting.pptx
  • 47:19 35.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 49:51 36.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 50:14 37.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 50:31 38.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 53:01 39.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 59:09 40.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 59:13 41.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 59:56 42.
    Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
  • 1:08:32 43.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:33 44.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:33 45.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:34 46.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:37 47.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:37 48.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:08:38 49.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:09:08 50.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:09:11 51.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:09:11 52.
    Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
  • 1:09:12 53.
    Summary
  • 1:09:14 54.
    circPDK1 functioned as a miR-628-3p sponge in PC
  • 1:09:14 55.
    circPDK1 functioned as a miR-628-3p sponge in PC
  • 1:09:15 56.
    circPDK1 functioned as a miR-628-3p sponge in PC
  • 1:09:15 57.
    circPDK1 acted as a ceRNA to modulate BPTF expression in PC
  • 1:09:17 58.
    ** after 20230703 lab meeting.pptx
  • Index
  • Notes
  • Comment
  • Fullscreen
20230703 lab meeting_怡君
Duration: 1:09:29, Browse: 131, Last Updated: 2023-07-20
    • 00:00 1.
      index 1
    • 00:24 2.
      Pancreatic cancer (PC)
    • 00:40 3.
      Hypoxia
    • 00:48 4.
      Pancreatic cancer (PC)
    • 00:49 5.
      Hypoxia
    • 01:18 6.
      Hypoxia-inducible factor 1-α (HIF-1a)
    • 01:19 7.
      Hypoxia
    • 02:12 8.
      Hypoxia-inducible factor 1-α (HIF-1a)
    • 02:18 9.
      Circular RNA (circRNA)
    • 02:19 10.
      Hypoxia-inducible factor 1-α (HIF-1a)
    • 02:26 11.
      Circular RNA (circRNA)
    • 02:26 12.
      Hypoxia-inducible factor 1-α (HIF-1a)
    • 02:27 13.
      Hypoxia
    • 02:27 14.
      Hypoxia-inducible factor 1-α (HIF-1a)
    • 03:34 15.
      Circular RNA (circRNA)
    • 06:13 16.
      Circular RNA (circRNA)
    • 06:33 17.
      Functions of circRNA
    • 07:46 18.
      MicroRNA (miRNA)
    • 11:54 19.
      Interplay between circRNA and miRNA
    • 13:46 20.
      Exosome
    • 14:16 21.
      Exosomal circRNA
    • 14:30 22.
      Exosomal circRNA
    • 14:42 23.
      Exosomal circRNA
    • 14:54 24.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 14:57 25.
      Exosomal circRNA
    • 15:02 26.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 21:28 27.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 24:17 28.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 24:18 29.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 29:08 30.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 35:40 31.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 42:15 32.
      Identification of circPDK1 as an exosomal biomarker for PC and characteristic of circPDK1
    • 45:14 33.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 47:08 34.
      ** after 20230703 lab meeting.pptx
    • 47:19 35.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 49:51 36.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 50:14 37.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 50:31 38.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 53:01 39.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 59:09 40.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 59:13 41.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 59:56 42.
      Exosomal circPDK1 was activated by HIF1A under hypoxic conditions
    • 1:08:32 43.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:33 44.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:33 45.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:34 46.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:37 47.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:37 48.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:08:38 49.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:09:08 50.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:09:11 51.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:09:11 52.
      Hypoxia-derived exosomal circPDK1 promoted PC cells proliferation and metastasis in vitro and in vivo
    • 1:09:12 53.
      Summary
    • 1:09:14 54.
      circPDK1 functioned as a miR-628-3p sponge in PC
    • 1:09:14 55.
      circPDK1 functioned as a miR-628-3p sponge in PC
    • 1:09:15 56.
      circPDK1 functioned as a miR-628-3p sponge in PC
    • 1:09:15 57.
      circPDK1 acted as a ceRNA to modulate BPTF expression in PC
    • 1:09:17 58.
      ** after 20230703 lab meeting.pptx
    Location
    Folder name
    2023
    Author
    黃照穎
    Branch
    賴亮全教授
    Created
    2023-07-20 10:34:48
    Last Updated
    2023-07-20 10:57:32
    Duration
    1:09:29