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00:00
1.
index 1
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14:20
2.
A microRNA-21–mediated SATB1/S100A9/NF-kBaxis promotes chronic obstructive pulmonarydisease pathogenesis
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14:47
3.
Slide 2
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15:54
4.
Classification of severity in COPD
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16:32
5.
The pulmonary function parameter
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16:32
6.
The Lung Function Test
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16:33
7.
The pulmonary function parameter
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16:33
8.
Classification of severity in COPD
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16:38
9.
The pulmonary function parameter
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22:17
10.
The Lung Function Test
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23:00
11.
White blood cells participates in airway inflammation
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23:56
12.
So, why the author chose miR-21 as a target gene?
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24:23
13.
CS induces lung miR-21 expression in COPD
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26:34
14.
miR-21 positive signals in the airway epithium
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26:36
15.
CS induces lung miR-21 expression in COPD
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31:56
16.
miR-21 positive signals in the airway epithium
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43:43
17.
Correlation between miR-21 expression and disease severity in COPD.
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53:44
18.
miR-21 expression in different phase of COPD
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54:15
19.
Summary
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54:43
20.
Inhibition of miR-21 suppresses airway inflammation.
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1:02:59
21.
The effectiveness of Ant-21 treatment in COPD
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1:04:44
22.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:06:31
23.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:09:50
24.
Summary
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1:10:14
25.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:10:15
26.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:10:31
27.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:10:32
28.
Summary
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1:10:32
29.
miR-21 reduces SATB1 responses
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1:10:33
30.
Summary
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1:10:34
31.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:10:34
32.
Summary
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1:10:37
33.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:10:38
34.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:12:14
35.
Inhibition of CS-induced lung miR-21 prevents the impairment of lung function
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1:12:14
36.
Summary
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1:12:15
37.
miR-21 reduces SATB1 responses
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1:13:08
38.
miR-21 reduces SATB1 responses
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1:13:45
39.
SATB1-siRNA abrogates Ant-21 treatment effect
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1:19:53
40.
Summary
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1:20:16
41.
miR-21 promotes lung S100A9 expression and NF-kB activity
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1:24:29
42.
The response of SABT1 and S100A9 in COPD progression
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1:24:30
43.
miR-21 promotes lung S100A9 expression and NF-kB activity
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1:24:33
44.
The response of SABT1 and S100A9 in COPD progression
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1:27:45
45.
The correlation of SABT1 and S1009A
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1:28:10
46.
Healthy vs. COPD & Scr vs. Ant Treatment
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1:30:26
47.
Features of disease progression in COPD
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1:32:23
48.
Conclusion