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[Publication list]
  • Bibliography in Pubmed
  • ORCID ID: 0000-0002-3913-5338
  • Academic Hub
  • ResearcherID: B-4768-2009
  • Scopus Author ID: 720261626
  • https://exaly.com/author/4269415/liang-chuan-lai/
  • SciVal
  1. C.-H. Chan, L.-H. Chen, K.-Y. Chen, I. H. Chen, K.-T. Lee, L.-C. Lai, M.-H. Tsai, E. Y. Chuang, M.-T. Lin, and T.-R. Yan. (2024). Single-strain probiotics enhance growth, anti-pathogen immunity, and resistance to Nocardia seriolae in grey mullet (Mugil cephalus) via gut microbiota modulation. Animal Microbiome, 6 5c187e820263b.png

  2. C.-H. S. Chen, T.-H. Yuan, T.-P. Lu, H.-Y. Lee, Y.-H. Chen, L.-C. Lai, M.-H. Tsai, E. Y. Chuang, and C.-C. Chan. (2024). Exposure-associated DNA methylation among people exposed to multiple industrial pollutants. Clinical Epigenetics, 16:111.5c187e820263b.png

  3. P.-L. Yang, T.-S. Lai, Y.-H. Chou, L.-C. Lai, S.-L. Lin, and Y.-M. Chen. (2024). DNA methylation in peripheral blood is associated with renal aging and renal function decline: a national community study. Clinical Epigenetics, 16:80. 5c187e820263b.png

  4. Y. Huang, T. Tsai, P. Ko, C. Huang, C. Chang, K. Chang, and L.C. Lai. (2024). The Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Diminished the Trau-matic Effects of HUVECs Injured by Indoxyl Sulfate. J Nephrol Renal Ther, 10:2.5c187e820263b.png

  5. Z.-Q. Hu, Y.-M. Hung, L.-H. Chen, L.-C. Lai, M.-H. Pan, E. Y. Chuang, and M.-H. Tsai. (2024). NURECON: A Novel Online System for Determining Nutrition Requirements Based on Microbial Composition. IEEE/ACM Transactions on Computational Biology and Bioinformatics.5c187e820263b.png

  6. A. Chattopadhyay, C. Y. Lee, Y. C. Lee, C. L. Liu, H. K. Chen, Y. H. Li, L. C. Lai, M. H. Tsai, Y. H. Ni, and H. M. Chiu. (2023). Twnbiome: a public database of the healthy Taiwanese gut microbiome. BMC Bioinformatics, 24:1.5c187e820263b.png

  7. T. Y. Lin, D. Jiang, W. R. Chen, J. S. Lin, X. Y. Zhang, C. H. Chen, C. L. Hsu, L. C. Lai, P. H. Chen, and K. C. Yang. (2023). Trained immunity induced by high‐salt diet impedes stroke recovery. EMBO reports:e57164.5c187e820263b.png

  8. W.-N. Lyu, M.-C. Lin, C.-Y. Shen, L.-H. Chen, Y.-H. Lee, S.-K. Chen, L.C. Lai, E. Y. Chuang, P.-J. Lou, and M.-H. Tsai. (2023). An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma. ACS Infectious Diseases, 9:1783. 5c187e820263b.png

  9. A. Chattopadhyay, C.-Y. Lee, Y.-C. Shen, K.-C. Lu, T.-H. Hsiao, C.-H. Lin, L.C. Lai., M.-H. Tsai, T.-P. Lu, and E. Y. Chuang. (2023). Multi-ethnic Imputation System (MI-System): A genotype imputation server for high-dimensional data. Journal of Biomedical Informatics, 143:104423.5c187e820263b.png

  10. T. Y. Wu, Y. T. Hsieh, Y. H. Wang, J. M. Chiou, T. F. Chen, L. C. Lai, J. H. Chen, and Y. C. Chen. (2023). The association between retinal vascular fractal dimension and cognitive function in the community-dwelling older adults cohort TIGER. J Formos Med Assoc, 10.1016/j.jfma.2023.04.001.5c187e820263b.png

  11. K.-Y. Lee, C.-M. Liu, L.-H. Chen, C.-Y. Lee, T.-P. Lu, L.-L. Chuang, and L.C. Lai. (2023). Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378 h. Cancer Cell International, 23:1. 5c187e820263b.png

  12. H.-H. Chao, J.-L. Luo, M.-H. Hsu, L.-H. Chen, T.-P. Lu, M.-H. Tsai, E. Y. Chuang, L.-L. Chuang, and L.C. Lai. (2022). Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells. Cell Death & Disease, 13:807.5c187e820263b.png

  13. Y.-P. Hsieh, Y.-M. Hung, M.-H. Tsai, L.C. Lai, and E. Y. Chuang. (2022). 16S-ITGDB: An Integrated Database for Improving Species Classification of Prokaryotic 16S Ribosomal RNA Sequences. Frontiers in Bioinformatics, 2. 5c187e820263b.png

  14. S. Shivani, C. Y. Kao, A. Chattopadhyay, J. W. Chen, L. C. Lai, W. H. Lin, T. P. Lu, I. H. Huang, M. H. Tsai, C. H. Teng, J. J. Wu, Y. H. Hsieh, M. C. Wang, and E. Y. Chuang. (2022). Uremic Toxin-Producing Bacteroides Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline. Front Cell Infect Microbiol, 12:726256.5c187e820263b.png

  15. Y. M. Hung, W. N. Lyu, M. L. Tsai, C. L. Liu, L. C. Lai, M. H. Tsai, and E. Y. Chuang. (2022). To compare the performance of prokaryotic taxonomy classifiers using curated 16S full-length rRNA sequences. Comput Biol Med, 145:105416.5c187e820263b.png

  16. M. Z. Chen, L. Y. Su, P. H. Ko, M. H. Hsu, L. L. Chuang, L. H. Chen, T. P. Lu, E. Y. Chuang, L. P. Chow, M. H. Tsai, H. H. Hsu, and L. C. Lai. (2022). Extracellular domain of semaphorin 5A serves a tumor‑suppressing role by activating interferon signaling pathways in lung adenocarcinoma cells. International Journal of Oncology, 60:1.5c187e820263b.png

  17. C. Lin, W. T. Tseng, Y. Y. Chang, M. H. Tsai, E. Y. Chuang, T. P. Lu, and L. C. Lai. (2022). Lidocaine and Bupivacaine Downregulate MYB and DANCR lncRNA by Upregulating miR-187-5p in MCF-7 Cells. Frontiers in Medicine, 8:2969.5c187e820263b.png

  18. Y.C. Huang, T.C. Tsai, C.H. Chang, K.T. Chang, P.H. Ko, L. C. Lai, Indoxyl Sulfate Elevated Lnc-SLC15A1-1 Upregulating CXCL10/CXCL8 Expression in High-Glucose Endothelial Cells by Sponging MicroRNAs. Toxins. 13 (2021) 873.5c187e820263b.png

  19. Y.H. Lin, J.M. Chiou, T.F. Chen, L. C. Lai, J.H. Chen, Y.C. Chen, The association between metabolic syndrome and successful aging- using an extended definition of successful aging. PLoS One. 16 (2021) e0260550.5c187e820263b.png

  20. W. Fang, C.H. Wu, Q. Sun, Z.T. Gu, L. Zhu, T. Mao, X.F. Zhang, N. Xu, T.P. Lu, M.H. Tsai, L.H. Chen, L. C. Lai, E.Y. Chuang, Novel Tumor-Specific Antigens for Immunotherapy Identified from Multi-omics Profiling in Thymic Carcinomas. Front Immunol.  4804. 5c187e820263b.png

  21. C.H. Lu, C.H. Wu, M.H. Tsai, L. C. Lai, E.Y. Chuang, MutScape: an analytical toolkit for probing the mutational landscape in cancer genomics. NAR genomics and bioinformatics. 3 (2021) lqab099. 5c187e820263b.png

  22. Chen JH, Shih HS, Tu J, Chiou JM, Chang SH, Hsu WL, L. C. Lai, Chen TF, and Chen YC. A Longitudinal Study on the Association of Interrelated Factors Among Frailty Dimensions, Cognitive Domains, Cognitive Frailty, and All-Cause Mortality. JOURNAL OF ALZHEIMER'S DISEASE. 2021. Oct 29.5c187e820263b.png

  23. Yu LCH, Wei SC, Li YH, Lin PY, Chang XY, Weng JP, Shue YW, L. C. Lai, Wang JT, and Jeng YM. Invasive Pathobionts Contribute to Colon Cancer Initiation by Counterbalancing Epithelial Antimicrobial Responses. Cellular and Molecular Gastroenterology and Hepatology. 2021. 5c187e820263b.png

  24. Lin YS, Kuo TT, Lo CC, Cheng WC, Chang WC, Tseng GC, Bai ST, Huang YK, Hsieh CY, Hsu HS, Jiang YF, Lin CY, L. C. Lai, Li XG, and Sher YP. ADAM9 functions as a transcriptional regulator to drive angiogenesis in esophageal squamous cell carcinoma. Int J Biol Sci. 2021. 17:3898-3910. 5c187e820263b.png

  25. Wu CH, Hsieh CS, Chang YC, Huang CC, Yeh HT, Hou MF, Chung YC, Tu SH, Chang KJ, Chattopadhyay A, L. C. Lai, Lu TP, Li YH, Tsai MH, and Chuang EY. Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population. Communication Biology. 2021. Sep 9; 4:1052.5c187e820263b.png

  26. Lee CY, Lee YF, L. C. Lai, Tsai MH, Lu TP, and Chuang EY. MiDSystem: A Comprehensive Online System for De Novo Assembly and Analysis of Microbial Genomes. New Biotechnology. 2021. 65:42-52.5c187e820263b.png

  27. Phan NN, Chattopadhyay A, Lee TT, Yin HI, Lu TP, L. C. Lai, Hwa HL, Tsai MH, and Chuang EY. High-performance deep learning pipeline predicts individuals in mixtures of DNA using sequencing data. Briefings in Bioinformatics. 2021. Aug 7.5c187e820263b.png

  28. Chattopadhyay A, Teoh ZH, Wu CY, Juang JJ, L. C. Lai, Tsai MH, Wu CH, Lu TP, and Chuang EY. CNVIntegrate: the first multi-ethnic database for identifying copy number variations associated with cancer. Database (Oxford). 2021. Jul 14; 2021.5c187e820263b.png

  29. Cheng YC, Su LY, Chen LH, Lu TP, Chuang EY, Tsai MH, Chuang LL, and L. C. Lai. Regulatory Mechanisms and Functional Roles of Hypoxia-Induced Long Non-Coding RNA MTORT1 in Breast Cancer Cells. Frontiers in Oncology. 2021. 11:663114.5c187e820263b.png

  30. Hung YM, Tsai MH, L. C. Lai, and Chuang EY. ATTRACTIVE – An Auto-Updating Database for Experimental Protocols in Regenerative Medicine. IEEE Access. 2021. 9:75202-75210.5c187e820263b.png

  31. Shih CH, Chuang LL, Tsai MH, Chen LH, Chuang EY, Lu TP, and L. C. Lai. Hypoxia-Induced MALAT1 Promotes the Proliferation and Migration of Breast Cancer Cells by Sponging MiR-3064-5p. Frontiers in Oncology. 2021. 11:658151.5c187e820263b.png

  32. Wu CH, Yeh HT, Hsieh CS, Huang CC, Chattopadhyay A, Chung YC, Tu SH, Li YH, Lu TP, L. C. Lai, Hou MF, Chang KJ, Tsai MH, and Chuang EY. Evolutionary Trajectories and Genomic Divergence in Localized Breast Cancers after Ipsilateral Breast Tumor Recurrence. Cancers (Basel). 2021. Apr 11; 13. 5c187e820263b.png

  33. Chin WY, He CY, Chow TW, Yu QY, L. C. Lai, and Miaw SC. Adenylate Kinase 4 Promotes Inflammatory Gene Expression via Hif1alpha and AMPK in Macrophages. Frontiers in Immunology. 2021. 12:630318.5c187e820263b.png

  34. Hung YM, Lu TP, Tsai MH, L. C. Lai, and Chuang EY. EasyMAP: A user-friendly online platform for analyzing 16S ribosomal DNA sequencing data. New Biotechnology. 2021. Mar 9; 63:37-44.5c187e820263b.png

  35. Y.M. Hung, L. C. Lai, Factors to be considered in designing frameworks for automated bioinformatics pipelines—a perspective based on application setting. Transl Cancer Res. 9 (2020) 7382-7383.5c187e820263b.png

  36. H. C. Lo, J. H. Hsu, L. C. Lai, M. H. Tsai, and E. Y. Chuang. (2020, Sep 3). MicroRNA-107 enhances radiosensitivity by suppressing granulin in PC-3 prostate cancer cells. Scientific Reports, 10:14584. 5c187e820263b.png

  37. Lin CC, Huang YK, Cho CF, Lin YS, Lo CC, Kuo TT, Tseng GC, Cheng WC, Chang WC, Hsiao TH, L. C. Lai, Shih JY, Liu YH, Chao KSC, Hsu JL, Lee PC, Sun X, Hung MC, and Sher YP. Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression. Theranostics. 2020. 10:10925-10939. 5c187e820263b.png

  38. Chou YH, Pan SY, Shao YH, Shih HM, Wei SY, Lai CF, Chiang WC, Schrimpf C, Yang KC, L. C. Lai, Chen YM, Chu TS, and Lin SL. Methylation in pericytes after acute injury promotes chronic kidney disease. The Journal of Clinical Investigation. 2020. Aug 4; 10.1172/JCI135773. 5c187e820263b.png

  39. Juang JJ, Binda A, Lee SJ, Hwang JJ, Chen WJ, Liu YB, Lin LY, Yu CC, Ho LT, Huang HC, Chen CJ, Lu TP, L. C. Lai, Yeh SS, Lai LP, Chuang EY, Rivolta I, and Antzelevitch C. GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death. EBioMedicine. 2020. Jul; 57:102843. 5c187e820263b.png

  40. Huang YS, L. C. Lai, Chen YA, Lin KY, Chou YH, Chen HC, Wang SS, Wang JT, and Chang SC. Colonization with multidrug-resistant organisms among healthy adults in the community setting: prevalence, risk factors, and composition of gut microbiome. Frontiers in Microbiology. 2020. Jun 24; 11:1402. 5c187e820263b.png

  41. Chen CH, Chen YF, Tsai PH, Chiou JM, L. C. Lai, Chen TF, Hung H, Chen JH, and Chen YC. Impacts of kidney dysfunction and cerebral cortical thinning on cognitive change in elderly population. Journal of Alzheimer's Disease. 2020. May 19. 5c187e820263b.png

  42. Chao KH, Hsiao YW, Lee YF, Lee CY, L. C. Lai, Tsai MH, Lu TP, and Chuang EY. RNASeqR: an R package for automated two-group RNA-Seq analysis workflow. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2019. Dec 2. 5c187e820263b.png

  43. W.C. Lin, L.H. Chen, Y.C. Hsieh, P.W. Yang, L. C. Lai, E.Y. Chuang, J.M. Lee, M.H. Tsai, miR-338-5p inhibits cell proliferation, colony formation, migration, and cisplatin resistance in esophageal squamous cancer cells by targeting FERMT2. Carcinogenesis. 40 (2019) 883-892.5c187e820263b.png

  44. Ko PH, Lenka G, Chen YA, Chuang EY, Tsai MH, Sher YP, and L. C. Lai. Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells. International Journal of Oncology. 2019. Dec 2:10.3892/ijo.2019.4932. 5c187e820263b.png

  45. Huang YC, and L. C. Lai. The potential roles of stem cell-derived extracellular vesicles as a therapeutic tool. Annals of Translational Medicine. 2019. Nov 10:10.21037/atm.2019.11.66. 5c187e820263b.png

  46. Wang CH, Chang RW, Wu ET, Hsiao YJ, Wu MS, Yu HY, Chen YS, L. C. Lai, and Yu SL. Extracorporeal life support enhances the forward pressure wave to cause a mismatch between cardiac oxygen demand and supply. Scientific Reports. 2019. Sep 25; 9:13882. 5c187e820263b.png

  47. Chen LH, Liao CY, L. C. Lai, Tsai MH, and Chuang EY. Semaphorin 6A attenuates the migration capability of lung cancer cells via the NRF2/HMOX1 axis. Scientific Reports. 2019. Sep 16; 9:13302. 5c187e820263b.png

  48. L. C. Lai, Sun QL, Chen YA, Hsiao YW, Lu TP, Tsai MH, Zhu L, Chuang EY, and Fang W. Using proteomic profiling to characterize protein signatures of different thymoma subtypes. BMC Cancer. 2019. Aug 13; 19:796. 5c187e820263b.png

  49. Wang TT, Lee CY, L. C. Lai, Tsai MH, Lu TP, and Chuang EY. anamiR: integrated analysis of MicroRNA and gene expression profiling. BMC Bioinformatics. 2019. May 14; 20:239. 5c187e820263b.png

  50. Ko PH, Huang CW, Chang HH, Chuang EY, Tsai MH, and L. C. Lai. Identifying the functions and biomarkers of Codonopsis pilosula and Astragalus membranaceus aqueous extracts in hepatic cells. Chinese Medicine. 2019. Mar; 14:10.5c187e820263b.png

  51. Ko PH, Shen YC, Murugan K, Huang CW, Sivakumar G, Pal P, Liao CC, Luo KS, Chuang EY, Tsai MH, and L. C. Lai. Macrophage migration inhibitory factor acts as the potential target of a newly synthesized compound, 1-(9′-methyl-3′-carbazole)-3, 4-dihydro-β-carboline. Scientific Reports. 2019. Feb 14; 9:2147. 5c187e820263b.png

  52. Lee CY, Chattopadhyay A, Chiang LM, Juang JJ, L. C. Lai, Tsai MH, Lu TP, and Chuang EY. VariED: the first integrated database of gene annotation and expression profiles for variants related to human diseases. Database (Oxford). 2019. Jan 1; 2019:10.1093/database/baz075. 5c187e820263b.png

  53. Shen CY, Chang YC, Chen LH, Lin WC, Lee YH, Yeh ST, Chen HK, Fang W, Hsu CP, Lee JM, Lu TP, Hsiao PW, L. C. Lai, Tsai MH, and Chuang EY. The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells. Oncogenesis. 2018. Dec 5; 7:95. 5c187e820263b.png
  54. Yeh CC, Luo JL, Nhut Phan N, Cheng YC, Chow LP, Tsai MH, Chuang EY, and L. C. Lai. Different effects of long noncoding RNA NDRG1-OT1 fragments on NDRG1 transcription in breast cancer cells under hypoxia. RNA Biology. 2018. Nov 30. 5c187e820263b.png
  55. Lee, C. Y., P. H. Hsieh, L. M. Chiang, A. Chattopadhyay, K. Y. Li, Y. F. Lee, T. P. Lu, L. C. Lai, E. C. Lin, H. Lee, S. T. Ding, M. H. Tsai, C. Y. Chen, and E. Y. Chuang. Whole-genome de novo sequencing reveals unique genes that contributed to the adaptive evolution of the Mikado pheasant. Gigascience. 2018. May 1; 7. 5c187e820263b.png
  56. Tseng, T. C., D. Y. Huang, L. C. Lai, H. Hwai, Y. W. Hsiao, J. P. Jhou, E. Y. Chuang, and S. J. Tzeng. Dual immuno-renal targeting of 7-benzylidenenaltrexone alleviates lupus nephritis via FcgammaRIIB and HO-1. Journal of Molecular Medicine. 2018. Mar; 10.1007/s00109-018-1626-9. 5c187e820263b.png
  57. Lin, H. C., C. C. Yeh, L. Y. Chao, M. H. Tsai, H. H. Chen, E. Y. Chuang, and L. C. Lai. The hypoxia-responsive lncRNA NDRG-OT1 promotes NDRG1 degradation via ubiquitin-mediated proteolysis in breast cancer cells. Oncotarget. 2018. Feb; 9:10470-10482. 5c187e820263b.png
  58.  Huang, S. H., Y. S. Chang, J. J. Juang, K. W. Chang, M. H. Tsai, T. P. Lu, L. C. Lai, E. Y. Chuang, and N. T. Huang. An automated microfluidic DNA microarray platform for genetic variant detection in inherited arrhythmic diseases. Analyst. 2018. Feb 9; 10.1039/c7an01648d.5c187e820263b.png
  59. Lee, Y. F., C. Y. Lee, L. C. Lai, M. H. Tsai, T. P. Lu, and E. Y. Chuang. CellExpress: a comprehensive microarray-based cancer cell line and clinical sample gene expression analysis online system. Database-the Journal of Biological Databases and Curation. 2018. Jan; 10.1093/database/bax101. 5c187e820263b.png
  60. Chang, Y. Y., L. C. Lai, M. H. Tsai, and E. Y. Chuang. Deep sequencing reveals a microRNA expression signature in triple-negative breast cancer. Methods in Molecular Biology. 2018. 1699:99-111. 5c187e820263b.png
  61. Wang, C. H., R. W. Chang, C. Y. Chang, M. S. Wu, H. L. Kao, L. C. Lai, T. H. Young, H. Y. Yu, Y. S. Chen, and K. C. Chang. Quantification of contractile mechanics in the rat heart from ventricular pressure alone. Oncotarget. 2017. Nov 10; 8:96161-96170. 5c187e820263b.png
  62. Lin, C. Y., C. F. Cho, S. T. Bai, J. P. Liu, T. T. Kuo, L. J. Wang, Y. S. Lin, C. C. Lin, L. C. Lai, T. P. Lu, C. Y. Hsieh, C. N. Chu, D. C. Cheng, and Y. P. Sher. ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. Scientific Reports. 2017. Nov; 7:15108. 5c187e820263b.png
  63. Wei, S. C., H. F. Yang-Yen, P. N. Tsao, M. T. Weng, C. C. Tung, L. C. H. Yu, L. C. Lai, J. H. Hsiao, E. Y. Chuang, C. T. Shun, Y. H. Ni, R. J. Xavier, D. K. Podolsky, J. J. Y. Yen, and J. M. Wong. SHANK3 regulates intestinal barrier function through modulating ZO-1 expression through the PKCepsilon-dependent pathway. Inflammatory Bowel Diseases. 2017. Oct; 23:1730-1740. 5c187e820263b.png
  64. Chiu, K. L., Y. S. Lin, T. T. Kuo, C. C. Lo, Y. K. Huang, H. F. Chang, E. Y. Chuang, C. C. Lin, W. C. Cheng, Y. N. Liu, L. C. Lai, and Y. P. Sher. ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis. Oncotarget. 2017. Jul; 8:47365-47378. 5c187e820263b.png
  65. Chang, C. Y., R. W. Chang, S. H. Hsu, M. S. Wu, Y. J. Cheng, H. L. Kao, L. C. Lai, C. H. Wang, and K. C. Chang. Defects in vascular mechanics due to aging in rats: studies on arterial wave properties from a single aortic pressure pulse. Frontiers in Physiology. 2017. Jul; 8:503. 5c187e820263b.png
  66. Lenka, G., M. H. Tsai, H. C. Lin, J. H. Hsiao, Y. C. Lee, T. P. Lu, J. M. Lee, C. P. Hsu, L. C. Lai, and E. Y. Chuang. Identification of methylation-driven, differentially expressed STXBP6 as a novel biomarker in lung adenocarcinoma. Scientific Reports. 2017. Feb; 7:42573. 5c187e820263b.png
  67. Chang, R. W., C. Y. Chang, L. C. Lai, M. S. Wu, T. H. Young, Y. S. Chen, C. H. Wang, and K. C. Chang. Determining arterial wave transit time from a single aortic pressure pulse in rats: vascular impulse response analysis. Scientific Reports. 2017. Jan; 7:40998. 5c187e820263b.png
  68. Lai, Y. P., L. B. Wang, W. A. Wang, L. C. Lai, M. H. Tsai, T. P. Lu, and E. Y. Chuang. iGC-an integrated analysis package of gene expression and copy number alteration. BMC Bioinformatics. 2017. Jan; 18:35. 5c187e820263b.png
  69. Shen, C. Y., L. H. Chen, Y. F. Lin, L. C. Lai, E. Y. Chuang, and M. H. Tsai. Mitomycin C treatment induces resistance and enhanced migration via phosphorylated Akt in aggressive lung cancer cells. Oncotarget. 2016. Nov; 7:79995-80007. 5c187e820263b.png
  70. Wang, W. A., L. C. Lai, M. H. Tsai, T. P. Lu, and E. Y. Chuang. Development of a prediction model for radiosensitivity using the expression values of genes and long non-coding RNAs. Oncotarget. 2016. May; 7:26739-50. 5c187e820263b.png
  71. Lenka, G., M. H. Tsai, J. H. Hsiao, L. C. Lai, and E. Y. Chuang. Overexpression of methylation-driven DCC suppresses proliferation of lung cancer cells. Translational Cancer Research. 2016. Apr; 5:169-175. 5c187e820263b.png
  72. Hsiao, T. H., Y. C. Chiu, P. Y. Hsu, T. P. Lu, L. C. Lai, M. H. Tsai, T. H. Huang, E. Y. Chuang, and Y. Chen. Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers. Scientific Reports. 2016. Mar; 6:23035. 5c187e820263b.png
  73. Chiu, Y. C., M. H. Tsai, W. C. Chou, Y. C. Liu, Y. Y. Kuo, H. A. Hou, T. P. Lu, L. C. Lai, Y. Chen, H. F. Tien, and E. Y. Chuang. Prognostic significance of NPM1 mutation-modulated microRNA-mRNA regulation in acute myeloid leukemia. Leukemia. 2016. Feb; 30:274-84. 5c187e820263b.png
  74. Li, E. Y., W. Y. Huang, Y. C. Chang, M. H. Tsai, E. Y. Chuang, Q. Y. Kuok, S. T. Bai, L. Y. Chao, Y. P. Sher, and L. C. Lai. Aryl hydrocarbon receptor activates NDRG1 transcription under hypoxia in breast cancer cells. Scientific Reports. 2016. Feb; 6:20808. 5c187e820263b.png
  75. Chang, R. W., C. Y. Chang, M. S. Wu, H. Y. Yu, J. M. Luo, Y. S. Chen, F. Y. Lin, L. C. Lai, C. H. Wang, and K. C. Chang. Systolic aortic pressure-time area is a useful index describing arterial wave properties in rats with diabetes. Scientific Reports. 2015. Dec; 5:17293. 5c187e820263b.png
  76. Chiu, K. L., T. T. Kuo, Q. Y. Kuok, Y. S. Lin, C. H. Hua, C. Y. Lin, P. Y. Su, L. C. Lai, and Y. P. Sher. ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis. Scientific Reports. 2015. Nov; 5:16426. 5c187e820263b.png
  77. Woolston, A., N. Sintupisut, T. P. Lu, L. C. Lai, M. H. Tsai, E. Y. Chuang, and C. H. Yeang. Putative effectors for prognosis in lung adenocarcinoma are ethnic and gender specific. Oncotarget. 2015. Aug; 6:19483-99. 5c187e820263b.png
  78. Kang, Y., Y. Y. Chang, Y. C. Liu, L. C. Lai, E. Y. Chuang, and M. H. Tsai. A microarray study of radiation-induced transcriptional responses and the role of Jagged 1 in two closely-related lung cancer cell lines. Translational Cancer Research. 2015. 4:314-323. 5c187e820263b.png
  79. Lu, T. P., C. K. Hsiao, L. C. Lai, M. H. Tsai, C. P. Hsu, J. M. Lee, and E. Y. Chuang. Identification of regulatory SNPs associated with genetic modifications in lung adenocarcinoma. BMC Research Notes. 2015. Mar; 8:92. 5c187e820263b.png
  80. Chang, Y. Y., W. H. Kuo, J. H. Hung, C. Y. Lee, Y. H. Lee, Y. C. Chang, W. C. Lin, C. Y. Shen, C. S. Huang, F. J. Hsieh, L. C. Lai, M. H. Tsai, K. J. Chang, and E. Y. Chuang. Deregulated microRNAs in triple-negative breast cancer revealed by deep sequencing. Molecular Cancer. 2015. Feb; 14:301. 5c187e820263b.png
  81. Juang, J. M., T. P. Lu, L. C. Lai, C. C. Ho, Y. B. Liu, C. T. Tsai, L. Y. Lin, C. C. Yu, W. J. Chen, F. T. Chiang, S. F. Yeh, L. P. Lai, E. Y. Chuang, and J. L. Lin. Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome. Scientific Reports. 2014. Oct; 4:6733. 5c187e820263b.png
  82. Huang, C. C., S. H. Tu, H. H. Lien, C. S. Huang, C. J. Huang, L. C. Lai, M. H. Tsai, and E. Y. Chuang. Refinement of breast cancer risk prediction with concordant leading edge subsets from prognostic gene signatures. Breast Cancer Research and Treatment. 2014. Sep; 147:353-70. 5c187e820263b.png
  83. Lin, C. Y., H. J. Chen, C. C. Huang, L. C. Lai, T. P. Lu, G. C. Tseng, T. T. Kuo, Q. Y. Kuok, J. L. Hsu, S. Y. Sung, M. C. Hung, and Y. P. Sher. ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway. Cancer Research. 2014. Sep; 74:5229-43. 5c187e820263b.png
  84. Lu, T. P., Y. Y. Hsu, L. C. Lai, M. H. Tsai, and E. Y. Chuang. Identification of gene expression biomarkers for predicting radiation exposure. Scientific Reports. 2014. Sep; 4:6293. 5c187e820263b.png
  85. Luo, E. C., Y. C. Chang, Y. P. Sher, W. Y. Huang, L. L. Chuang, Y. C. Chiu, M. H. Tsai, E. Y. Chuang, and L. C. Lai. MicroRNA-769-3p down-regulates NDRG1 and enhances apoptosis in MCF-7 cells during reoxygenation. Scientific Reports. 2014. Aug; 4:5908. 5c187e820263b.png
  86. Wei, S. C., Y. Y. Tan, M. T. Weng, L. C. Lai, J. H. Hsiao, E. Y. Chuang, C. T. Shun, D. C. Wu, A. W. Kao, C. S. Chuang, Y. H. Ni, M. J. Shieh, C. C. Tung, Y. Chen, C. Y. Wang, R. J. Xavier, D. K. Podolsky, and J. M. Wong. SLCO3A1, a novel Crohn's disease-associated gene, regulates NF-kappaB activity and associates with intestinal perforation. PLoS One. 2014. Jun; 9:e100515. 5c187e820263b.png
  87. Sher, Y. P., L. J. Wang, L. L. Chuang, M. H. Tsai, T. T. Kuo, C. C. Huang, E. Y. Chuang, and L. C. Lai. ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells. PLoS One. 2014. Apr; 9:e94065. 5c187e820263b.png
  88. L. C. Lai, M. H. Tsai, P. C. Chen, L. H. Chen, J. H. Hsiao, S. K. Chen, T. P. Lu, J. M. Lee, C. P. Hsu, C. K. Hsiao, and E. Y. Chuang. SNP rs10248565 in HDAC9 as a novel genomic aberration biomarker of lung adenocarcinoma in non-smoking women. Journal of Biomedical Science. 2014. Mar; 21:24. 5c187e820263b.png
  89. Lu, T. P., K. T. Chen, M. H. Tsai, K. T. Kuo, C. K. Hsiao, L. C. Lai, and E. Y. Chuang. Identification of genes with consistent methylation levels across different human tissues. Scientific Reports. 2014. Mar; 4:4351. 5c187e820263b.png
  90. Huang, C. C., S. H. Tu, H. H. Lien, J. Y. Jeng, J. S. Liu, C. S. Huang, L. C. Lai, and E. Y. Chuang. Estrogen receptor status prediction by gene component regression: a comparative study. International Journal of Data Mining and Bioinformatics. 2014. Feb; 9:149-71. 5c187e820263b.png
  91. Juang, J. M., T. P. Lu, L. C. Lai, C. H. Hsueh, Y. B. Liu, C. T. Tsai, L. Y. Lin, C. C. Yu, J. J. Hwang, F. T. Chiang, S. S. Yeh, W. P. Chen, E. Y. Chuang, L. P. Lai, and J. L. Lin. Utilizing multiple in silico analyses to identify putative causal SCN5A variants in Brugada syndrome. Scientific Reports. 2014. Jan; 4:3850. 5c187e820263b.png
  92. Huang, C. C., S. H. Tu, C. S. Huang, H. H. Lien, L. C. Lai, and E. Y. Chuang. Multiclass prediction with partial least square regression for gene expression data: applications in breast cancer intrinsic taxonomy. BioMed Research International. 2013. Nov; 2013:1-9. 5c187e820263b.png
  93. Huang, C. C., S. H. Tu, H. H. Lien, J. Y. Jeng, C. S. Huang, C. J. Huang, L. C. Lai, and E. Y. Chuang. Concurrent gene signatures for Han Chinese breast cancers. PLoS One. 2013. Oct; 8:e76421. 5c187e820263b.png
  94. Lai, T. Y., S. D. Wu, M. H. Tsai, E. Y. Chuang, L. L. Chuang, L. C. Hsu, and L. C. Lai. Transcription of Tnfaip3 is regulated by NF-kappaB and p38 via C/EBPbeta in activated macrophages. PLoS One. 2013. Sep; 8:e73153. 5c187e820263b.png
  95. Chen, P. C., T. P. Lu, J. C. Chang,L. C. Lai, M. H. Tsai, C. K. Hsiao, and E. Y. Chuang. Concurrent analysis of copy number variation and gene expression: application in paired non-smoking female lung cancer patients. International Journal of Data Mining and Bioinformatics. 2013. Jul; 8:92-104. 5c187e820263b.png
  96. Wu, F. C., L. C. Lai, Y. H. Kuo, Y. H. Lee, F. H. Hsu, C. Y. Shen, E. Y. Chuang, and M. H. Tsai. Differential genomic alterations in normal and cancerous lung cells in response to chronic inflammation. Translational Cancer Research. 2013. Apr; 2:64-73. 5c187e820263b.png
  97. Liu, Y. J., Y. F. Lin, Y. F. Chen, E. C. Luo, Y. P. Sher, M. H. Tsai, E. Y. Chuang, and L. C. Lai. MicroRNA-449a enhances radiosensitivity in CL1-0 lung adenocarcinoma cells. PLoS One. 2013. Apr; 8:e62383. 5c187e820263b.png
  98. Huang, C. C., J. Y. Jeng, S. H. Tu, H. H. Lien, C. S. Huang, L. C. Lai, and E. Y. Chuang. A preliminary study of concurrent gains and losses across gene expression profiles and comparative genomic hybridization in Taiwanese breast cancer patients. Translational Cancer Research. 2013. Feb; 2:18-24. 5c187e820263b.png
  99. L. C. Lai Using gene set signature to guide hypothesis-driven experiments. Translational Cancer Research. 2013. Feb; 2:1-2. 5c187e820263b.png
  100. Lee, C. H., Y. C. Chiu, L. B. Wang, Y. L. Kuo, E. Y. Chuang, L. C. Lai, and M. H. Tsai. Common applications of next-generation sequencing technologies in genomic research. Translational Cancer Research. 2013. Feb; 2:33-45. 5c187e820263b.png
  101. Lin, S. Y., S. C. Hsieh, Y. C. Lin, C. N. Lee, M. H. Tsai, L. C. Lai, E. Y. Chuang, P. C. Chen, C. C. Hung, L. Y. Chen, W. S. Hsieh, D. M. Niu, Y. N. Su, and H. N. Ho. A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity. Genes Immunity. 2012. Nov; 13:214. 5c187e820263b.png
  102. Huang, C. C., S. H. Tu, H. H. Lien, J. Y. Jeng, J. S. Liu, C. S. Huang, Y. Y. Wu, C. Y. Liu, L. C. Lai, and E. Y. Chuang. Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population. Journal of Translational Medicine. 2012. Sep; 10 Suppl 1:S10. 5c187e820263b.png
  103. Kuo, W. H., Y. Y. Chang, L. C. Lai, M. H. Tsai, C. K. Hsiao, K. J. Chang, and E. Y. Chuang. Molecular characteristics and metastasis predictor genes of triple-negative breast cancer: a clinical study of triple-negative breast carcinomas. PLoS One. 2012. Sep; 7:e45831. 5c187e820263b.png
  104. Lu, T. P., C. Y. Lee, M. H. Tsai, Y. C. Chiu, C. K. Hsiao, L. C. Lai, and E. Y. Chuang. miRSystem: An integrated system for characterizing enriched functions and pathways of microRNA targets. PLoS One. 2012. Aug; 7:e42390. 5c187e820263b.png
  105. Chen, P. C., Y. C. Chen, L. C. Lai, M. H. Tsai, S. K. Chen, P. W. Yang, Y. C. Lee, C. K. Hsiao, J. M. Lee, and E. Y. Chuang. Use of germline polymorphisms in predicting concurrent chemoradiotherapy response in esophageal cancer. International Journal of Radiation Oncology • Biology • Physics. 2012. May; 82:1996-2003. 5c187e820263b.png
  106. Lu, T. P., M. H. Tsai, C. K. Hsiao, L. C. Lai, and E. Y. Chuang. Expression and functions of semaphorins in cancer. Translational Cancer Research. 2012. Apr; 1:74-78. 5c187e820263b.png
  107. Chen, S. Y., T. F. Chen, L. C. Lai, J. H. Chen, Y. Sun, L. L. Wen, P. K. Yip, Y. M. Chu, and Y. C. Chen. Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease. Journal of Neuroinflammation. 2012. Jan; 9:21. 5c187e820263b.png
  108. Chen, Y. C., L. C. Lai, Y. P. Tu, S. D. Wu, C. F. Chen, and B. Li. Far infrared ray irradiation attenuates apoptosis and cell death of cultured keratinocytes stressed by dehydration. Journal of Photochemistry and Photobiology B: Biology. 2012. Jan; 106:61-8. 5c187e820263b.png
  109. Cheng, H. C., Y. Sun, L. C. Lai, S. Y. Chen, W. C. Lee, J. H. Chen, T. F. Chen, H. H. Chen, L. L. Wen, P. K. Yip, Y. M. Chu, W. J. Chen, and Y. C. Chen. Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease. Journal of Negative Results in BioMedicine. 2012. Jan; 11:5. 5c187e820263b.png
  110. Lin, Y. L., S. Y. Chen, L. C. Lai, J. H. Chen, S. Y. Yang, Y. L. Huang, T. F. Chen, Y. Sun, L. L. Wen, P. K. Yip, Y. M. Chu, W. J. Chen, and Y. C. Chen. Genetic polymorphisms of clusterin gene are associated with a decreased risk of Alzheimer's disease. European Journal of Epidemiology. 2012. Jan; 27:73-75. 5c187e820263b.png
  111. Chen, L. H., W. H. Kuo, M. H. Tsai, P. C. Chen, C. K. Hsiao, E. Y. Chuang, L. Y. Chang, F. J. Hsieh, L. C. Lai, and K. J. Chang. Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan. PLoS One. 2011. Nov; 6:e28222. 5c187e820263b.png
  112. Hsu, F. H., H. I. Chen, M. H. Tsai, L. C. Lai, C. C. Huang, S. H. Tu, E. Y. Chuang, and Y. Chen. A model-based circular binary segmentation algorithm for the analysis of array CGH data. BMC Research Notes. 2011. Oct.; 4:394. 5c187e820263b.png
  113. Lu, T. P., L. C. Lai, M. H. Tsai, P. C. Chen, C. P. Hsu, J. M. Lee, C. K. Hsiao, and E. Y. Chuang. Integrated analyses of copy number variations and gene expression in lung adenocarcinoma. PLoS One. 2011. Sep; 6:e24829. 5c187e820263b.png
  114. L. C. Lai, Y. Y. Su, K. C. Chen, M. H. Tsai, Y. P. Sher, T. P. Lu, C. Y. Lee, and E. Y. Chuang. Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation. PLoS One. 2011. Aug; 6:e24375. 5c187e820263b.png
  115. Kuo, H. C., P. Y. Lin, T. C. Chung, C. M. Chao, L. C. Lai, M. H. Tsai, and E. Y. Chuang. DBCAT: Database of CpG islands and analytical tools for identifying comprehensive methylation profiles in cancer cells. Journal of Computational Biology. 2011. Aug; 18:1013-7. 5c187e820263b.png
  116. Lin, K. P., S. Y. Chen, L. C. Lai, Y. L. Huang, J. H. Chen, T. F. Chen, Y. Sun, L. L. Wen, P. K. Yip, Y. M. Chu, W. J. Chen, and Y. C. Chen. Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's disease. PLoS One. 2011. Jun.; 6:e20573. 5c187e820263b.png
  117. Hsu, L. C., T. Enzler, J. Seita, A. M. Timmer, C. Y. Lee, T. Y. Lai, G. Y. Yu, L. C. Lai, V. Temkin, U. Sinzig, T. Aung, V. Nizet, I. L. Weissman, and M. Karin. IL-1beta-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKbeta. Nature Immunology. 2011. Feb; 12:144-50. 5c187e820263b.png
  118. Lu, T. P., M. H. Tsai, J. M. Lee, C. P. Hsu, P. C. Chen, C. W. Lin, J. Y. Shih, P. C. Yang, C. K. Hsiao, L. C. Lai, and E. Y. Chuang. Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women. Cancer Epidemiology, Biomarkers & Prevention. 2010. Oct; 19:2590-7. 5c187e820263b.png
  119. Lu, T. P., L. C. Lai, B. I. Lin, L. H. Chen, T. H. Hsiao, H. L. Liber, J. A. Cook, J. B. Mitchell, M. H. Tsai, and E. Y. Chuang. Distinct signaling pathways after higher or lower doses of radiation in three closely related human lymphoblast cell lines. International Journal of Radiation Oncology • Biology • Physics. 2010. Jan; 76:212-9. 5c187e820263b.png
  120. L. C. Lai, M. T. Kissinger, P. V. Burke, and K. E. Kwast. Comparison of the transcriptomic "stress response" evoked by antimycin A and oxygen deprivation in Saccharomyces cerevisiae. BMC Genomics. 2008. Dec; 9:627. 5c187e820263b.png
  121. L. C. Lai, A. L. Kosorukoff, P. V. Burke, and K. E. Kwast. Metabolic-state-dependent remodeling of the transcriptome in response to anoxia and subsequent reoxygenation in Saccharomyces cerevisiae. Eukaryotic Cell. 2006. Sep; 5:1468-89. 5c187e820263b.png
  122. L. C. Lai, A. L. Kosorukoff, P. V. Burke, and K. E. Kwast. Dynamical remodeling of the transcriptome during short-term anaerobiosis in Saccharomyces cerevisiae: differential response and role of Msn2 and/or Msn4 and other factors in galactose and glucose media. Molecular and Cellular Biology. 2005. May; 25:4075-91. 5c187e820263b.png
  123. Burke, P. V., L. C. Lai, and K. E. Kwast. A rapid filtration apparatus for harvesting cells under controlled conditions for use in genome-wide temporal profiling studies. Analytical Biochemistry. 2004. May; 328:29-34. 5c187e820263b.png
  124. Kwast, K. E., L. C. Lai, N. Menda, D. T. James, 3rd, S. Aref, and P. V. Burke. Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. Journal of Bacteriology. 2002. Jan; 184:250-65. 5c187e820263b.png
  125. Lai, Y. L., S. C. Lee, L. C. Lai, F. C. Hu, T. L. Tsai, and Y. F. Tsai. Catecholamines in hyperpnoea-induced airway constriction of guinea pigs. Journal of Autonomic Pharmacology. 2001. Jun; 21:151-7. 5c187e820263b.png
  126. Lai, Y. L., C. W. Lin, and L. C. Lai. Attenuation of isocapnic hyperpnoea-induced guinea-pig bronchoconstriction by chronic hypoxia. European Respiratory Journal. 1998. May; 11:1075-80. 5c187e820263b.png

學術著作

[Publication list]
  • Bibliography in Pubmed
  • ORCID ID: 0000-0002-3913-5338
  • Academic Hub
  • ResearcherID: B-4768-2009
  • Scopus Author ID: 720261626
  • https://exaly.com/author/4269415/liang-chuan-lai/
  • SciVal
  1. C.-H. Chan, L.-H. Chen, K.-Y. Chen, I. H. Chen, K.-T. Lee, L.-C. Lai, M.-H. Tsai, E. Y. Chuang, M.-T. Lin, and T.-R. Yan. (2024). Single-strain probiotics enhance growth, anti-pathogen immunity, and resistance to Nocardia seriolae in grey mullet (Mugil cephalus) via gut microbiota modulation. Animal Microbiome, 6 5c187e820263b.png

  2. C.-H. S. Chen, T.-H. Yuan, T.-P. Lu, H.-Y. Lee, Y.-H. Chen, L.-C. Lai, M.-H. Tsai, E. Y. Chuang, and C.-C. Chan. (2024). Exposure-associated DNA methylation among people exposed to multiple industrial pollutants. Clinical Epigenetics, 16:111.5c187e820263b.png

  3. P.-L. Yang, T.-S. Lai, Y.-H. Chou, L.-C. Lai, S.-L. Lin, and Y.-M. Chen. (2024). DNA methylation in peripheral blood is associated with renal aging and renal function decline: a national community study. Clinical Epigenetics, 16:80. 5c187e820263b.png

  4. Y. Huang, T. Tsai, P. Ko, C. Huang, C. Chang, K. Chang, and L.C. Lai. (2024). The Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Diminished the Trau-matic Effects of HUVECs Injured by Indoxyl Sulfate. J Nephrol Renal Ther, 10:2.5c187e820263b.png

  5. Z.-Q. Hu, Y.-M. Hung, L.-H. Chen, L.-C. Lai, M.-H. Pan, E. Y. Chuang, and M.-H. Tsai. (2024). NURECON: A Novel Online System for Determining Nutrition Requirements Based on Microbial Composition. IEEE/ACM Transactions on Computational Biology and Bioinformatics.5c187e820263b.png

  6. A. Chattopadhyay, C. Y. Lee, Y. C. Lee, C. L. Liu, H. K. Chen, Y. H. Li, L. C. Lai, M. H. Tsai, Y. H. Ni, and H. M. Chiu. (2023). Twnbiome: a public database of the healthy Taiwanese gut microbiome. BMC Bioinformatics, 24:1.5c187e820263b.png

  7. T. Y. Lin, D. Jiang, W. R. Chen, J. S. Lin, X. Y. Zhang, C. H. Chen, C. L. Hsu, L. C. Lai, P. H. Chen, and K. C. Yang. (2023). Trained immunity induced by high‐salt diet impedes stroke recovery. EMBO reports:e57164.5c187e820263b.png

  8. W.-N. Lyu, M.-C. Lin, C.-Y. Shen, L.-H. Chen, Y.-H. Lee, S.-K. Chen, L.C. Lai, E. Y. Chuang, P.-J. Lou, and M.-H. Tsai. (2023). An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma. ACS Infectious Diseases, 9:1783. 5c187e820263b.png

  9. A. Chattopadhyay, C.-Y. Lee, Y.-C. Shen, K.-C. Lu, T.-H. Hsiao, C.-H. Lin, L.C. Lai., M.-H. Tsai, T.-P. Lu, and E. Y. Chuang. (2023). Multi-ethnic Imputation System (MI-System): A genotype imputation server for high-dimensional data. Journal of Biomedical Informatics, 143:104423.5c187e820263b.png

  10. T. Y. Wu, Y. T. Hsieh, Y. H. Wang, J. M. Chiou, T. F. Chen, L. C. Lai, J. H. Chen, and Y. C. Chen. (2023). The association between retinal vascular fractal dimension and cognitive function in the community-dwelling older adults cohort TIGER. J Formos Med Assoc, 10.1016/j.jfma.2023.04.001.5c187e820263b.png

  11. K.-Y. Lee, C.-M. Liu, L.-H. Chen, C.-Y. Lee, T.-P. Lu, L.-L. Chuang, and L.C. Lai. (2023). Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378 h. Cancer Cell International, 23:1. 5c187e820263b.png

  12. H.-H. Chao, J.-L. Luo, M.-H. Hsu, L.-H. Chen, T.-P. Lu, M.-H. Tsai, E. Y. Chuang, L.-L. Chuang, and L.C. Lai. (2022). Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells. Cell Death & Disease, 13:807.5c187e820263b.png

  13. Y.-P. Hsieh, Y.-M. Hung, M.-H. Tsai, L.C. Lai, and E. Y. Chuang. (2022). 16S-ITGDB: An Integrated Database for Improving Species Classification of Prokaryotic 16S Ribosomal RNA Sequences. Frontiers in Bioinformatics, 2. 5c187e820263b.png

  14. S. Shivani, C. Y. Kao, A. Chattopadhyay, J. W. Chen, L. C. Lai, W. H. Lin, T. P. Lu, I. H. Huang, M. H. Tsai, C. H. Teng, J. J. Wu, Y. H. Hsieh, M. C. Wang, and E. Y. Chuang. (2022). Uremic Toxin-Producing Bacteroides Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline. Front Cell Infect Microbiol, 12:726256.5c187e820263b.png

  15. Y. M. Hung, W. N. Lyu, M. L. Tsai, C. L. Liu, L. C. Lai, M. H. Tsai, and E. Y. Chuang. (2022). To compare the performance of prokaryotic taxonomy classifiers using curated 16S full-length rRNA sequences. Comput Biol Med, 145:105416.5c187e820263b.png

  16. M. Z. Chen, L. Y. Su, P. H. Ko, M. H. Hsu, L. L. Chuang, L. H. Chen, T. P. Lu, E. Y. Chuang, L. P. Chow, M. H. Tsai, H. H. Hsu, and L. C. Lai. (2022). Extracellular domain of semaphorin 5A serves a tumor‑suppressing role by activating interferon signaling pathways in lung adenocarcinoma cells. International Journal of Oncology, 60:1.5c187e820263b.png

  17. C. Lin, W. T. Tseng, Y. Y. Chang, M. H. Tsai, E. Y. Chuang, T. P. Lu, and L. C. Lai. (2022). Lidocaine and Bupivacaine Downregulate MYB and DANCR lncRNA by Upregulating miR-187-5p in MCF-7 Cells. Frontiers in Medicine, 8:2969.5c187e820263b.png

  18. Y.C. Huang, T.C. Tsai, C.H. Chang, K.T. Chang, P.H. Ko, L. C. Lai, Indoxyl Sulfate Elevated Lnc-SLC15A1-1 Upregulating CXCL10/CXCL8 Expression in High-Glucose Endothelial Cells by Sponging MicroRNAs. Toxins. 13 (2021) 873.5c187e820263b.png

  19. Y.H. Lin, J.M. Chiou, T.F. Chen, L. C. Lai, J.H. Chen, Y.C. Chen, The association between metabolic syndrome and successful aging- using an extended definition of successful aging. PLoS One. 16 (2021) e0260550.5c187e820263b.png

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