• 00:00 1.
    index 1
  • 00:20 2.
    Long non-coding RNA (lncRNA)
  • 00:56 3.
    Functions of lncRNA
  • 02:08 4.
    Colorectal Neoplasia Differentially Expressed (CRNDE)
  • 02:48 5.
    Wnt Pathway
  • 03:40 6.
    Wnt/β-catenin Signaling Pathway
  • 05:05 7.
    Results
  • 05:08 8.
    CRNDE expression is elevated in CRC tissue
  • 07:05 9.
    CRNDE binds to miR-181a-5p and represses its expression
  • 10:10 10.
    CRNDE binds to miR-181a-5p and represses its expression
  • 10:56 11.
    CRNDE binds to miR-181a-5p and represses its expression
  • 11:57 12.
    Slide 12
  • 12:05 13.
    CRNDE promotes CRC cell proliferation
  • 12:15 14.
    CRNDE promotes CRC cell proliferation
  • 12:16 15.
    CRNDE promotes CRC cell proliferation
  • 13:10 16.
    CRNDE promotes CRC cell proliferation
  • 13:55 17.
    CRNDE promotes CRC chemoresistance
  • 15:01 18.
    CRNDE promotes CRC chemoresistance
  • 15:30 19.
    CRNDE promotes CRC chemoresistance
  • 16:11 20.
    X
  • 16:32 21.
    Slide 19
  • 16:44 22.
    MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
  • 18:40 23.
    MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
  • 20:49 24.
    Knocking down β-catenin and TCF4 inhibits chemoresistance
  • 20:50 25.
    MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
  • 21:02 26.
    Knocking down β-catenin and TCF4 inhibits chemoresistance
  • 22:17 27.
    CRNDE
  • 22:49 28.
    Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
  • 25:40 29.
    Summary
  • 25:41 30.
    Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
  • 25:43 31.
    Summary
  • 25:44 32.
    Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
  • 25:45 33.
    Summary
  • 26:50 34.
    Comments
  • 28:06 35.
    ** after seminar.pptx
  • 28:27 36.
    Long non-coding RNA (lncRNA)
  • 28:28 37.
    Functions of lncRNA
  • 28:30 38.
    ** after seminar.pptx
  • 29:24 39.
    CRNDE binds to miR-181a-5p and represses its expression
  • 29:45 40.
    CRNDE binds to miR-181a-5p and represses its expression
  • 29:45 41.
    CRNDE binds to miR-181a-5p and represses its expression
  • 29:46 42.
    CRNDE binds to miR-181a-5p and represses its expression
  • 30:05 43.
    ** after seminar.pptx
  • 30:12 44.
    Summary
  • 39:09 45.
    ** after seminar.pptx
  • 39:14 46.
    CRNDE expression is elevated in CRC tissue
  • 41:01 47.
    ** after seminar.pptx
  • Index
  • Notes
  • Comment
  • Fullscreen
20190513-lab meeting_冠儀
Duration: 41:07, Browse: 638, Last Updated: 2019-06-13
Keypoint
  1. 1.
    a7a16e39de4939c692dfe4c8620b91f0.png
    • 00:00 1.
      index 1
    • 00:20 2.
      Long non-coding RNA (lncRNA)
    • 00:56 3.
      Functions of lncRNA
    • 02:08 4.
      Colorectal Neoplasia Differentially Expressed (CRNDE)
    • 02:48 5.
      Wnt Pathway
    • 03:40 6.
      Wnt/β-catenin Signaling Pathway
    • 05:05 7.
      Results
    • 05:08 8.
      CRNDE expression is elevated in CRC tissue
    • 07:05 9.
      CRNDE binds to miR-181a-5p and represses its expression
    • 10:10 10.
      CRNDE binds to miR-181a-5p and represses its expression
    • 10:56 11.
      CRNDE binds to miR-181a-5p and represses its expression
    • 11:57 12.
      Slide 12
    • 12:05 13.
      CRNDE promotes CRC cell proliferation
    • 12:15 14.
      CRNDE promotes CRC cell proliferation
    • 12:16 15.
      CRNDE promotes CRC cell proliferation
    • 13:10 16.
      CRNDE promotes CRC cell proliferation
    • 13:55 17.
      CRNDE promotes CRC chemoresistance
    • 15:01 18.
      CRNDE promotes CRC chemoresistance
    • 15:30 19.
      CRNDE promotes CRC chemoresistance
    • 16:11 20.
      X
    • 16:32 21.
      Slide 19
    • 16:44 22.
      MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
    • 18:40 23.
      MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
    • 20:49 24.
      Knocking down β-catenin and TCF4 inhibits chemoresistance
    • 20:50 25.
      MiR-181a-5p targets β-catenin/TCF4 and inhibits Wnt/β-catenin signaling
    • 21:02 26.
      Knocking down β-catenin and TCF4 inhibits chemoresistance
    • 22:17 27.
      CRNDE
    • 22:49 28.
      Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
    • 25:40 29.
      Summary
    • 25:41 30.
      Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
    • 25:43 31.
      Summary
    • 25:44 32.
      Regulation of CRC cell proliferation, chemoresistance and Wnt/β-catenin signaling by CRNDE requires miR-181a-5p
    • 25:45 33.
      Summary
    • 26:50 34.
      Comments
    • 28:06 35.
      ** after seminar.pptx
    • 28:27 36.
      Long non-coding RNA (lncRNA)
    • 28:28 37.
      Functions of lncRNA
    • 28:30 38.
      ** after seminar.pptx
    • 29:24 39.
      CRNDE binds to miR-181a-5p and represses its expression
    • 29:45 40.
      CRNDE binds to miR-181a-5p and represses its expression
    • 29:45 41.
      CRNDE binds to miR-181a-5p and represses its expression
    • 29:46 42.
      CRNDE binds to miR-181a-5p and represses its expression
    • 30:05 43.
      ** after seminar.pptx
    • 30:12 44.
      Summary
    • 39:09 45.
      ** after seminar.pptx
    • 39:14 46.
      CRNDE expression is elevated in CRC tissue
    • 41:01 47.
      ** after seminar.pptx
    Location
    Folder name
    2019
    Author
    鄭捷登
    Branch
    賴亮全教授
    Created
    2019-05-13 09:58:40
    Last Updated
    2019-06-13 12:52:33
    Duration
    41:07