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00:35
1.
index 1
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00:01
2.
Slide 2
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00:24
3.
Gastric Cancer
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00:41
4.
Risk factors of gastric cancer
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01:04
5.
RNA methylation (N6-methyladenosine modification, m6A)
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01:09
6.
Alteration of RNA m6A modification participates in the progression of gastric cancer
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00:39
7.
The relationship between demethylase and gastric cancer is still unclear……
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00:16
8.
Aims of the study
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00:02
9.
Slide 9
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00:34
10.
Methylated RNA immunoprecipitation sequencing of gastric cancer tissue
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00:42
11.
Workflow of meRIP-seq and data analysis
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00:31
12.
Methylated RNA immunoprecipitation sequencing of gastric cancer tissue
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01:09
13.
Methylated RNA immunoprecipitation sequencing of gastric cancer tissue
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00:28
14.
The expression level of ALKBH5 in gastric cancer tissues
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00:41
15.
The expression level of ALKBH5 in gastric cancer tissues
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00:38
16.
The functions of ALKBH5 in gastric cancer cells
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01:27
17.
The functions of ALKBH5 in gastric cancer cells
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00:23
18.
Summary-1
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01:06
19.
Investigate the downstream target of ALKBH5
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00:24
20.
Investigate the downstream target of ALKBH5
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00:00
21.
The role of PKMYT1
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00:13
22.
Investigate the downstream target of ALKBH5
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00:57
23.
The role of PKMYT1
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00:44
24.
The impact of PKMYT1 m6A modification
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00:16
25.
The impact of PKMYT1 m6A modification
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00:37
26.
The impact of PKMYT1 m6A modification
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00:18
27.
Summary-2
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00:34
28.
Results
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00:34
29.
Investigate the potential “reader” protein of PKMYT1
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01:24
30.
Investigate the potential “reader” protein of PKMYT1
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00:35
31.
Detect tumor lung metastasis in vivo
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00:46
32.
Results
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00:39
33.
Comments
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00:18
34.
Comments
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00:09
35.
Thank you
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20:33
36.
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