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00:03
1.
index 1
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00:07
2.
Slide 1
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05:12
3.
CircMET expression is significantly increased in NONO‑TFE3 tRCC
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02:04
4.
Characterization of CircMET in NONO‑TFE3 tRCC
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02:35
5.
CircMET is predominantly located in the cytosol
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00:02
6.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:55
7.
CircMET is predominantly located in the cytosol
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02:29
8.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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01:26
9.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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01:03
10.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:01
11.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:04
12.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:03
13.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:52
14.
CircMET accelerates proliferation of NONO‑TFE3 tRCC
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00:12
15.
Slide 8
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20:57
16.
NONO-TFE3 directly interacted with the promoter of MET
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00:05
17.
NONO-TFE3 promotes tumor progression by upregulating circMET
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01:12
18.
NONO-TFE3 directly interacted with the promoter of MET
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00:06
19.
NONO-TFE3 promotes tumor progression by upregulating circMET
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00:03
20.
Slide 11
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22:28
21.
CircMET is exported to cytoplasm by YTHDC1 in m6A‑depend manner
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02:18
22.
CircMET is exported to cytoplasm by YTHDC1 in m6A‑depend manner
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00:00
23.
CircMET
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04:01
24.
CircMET is exported to cytoplasm by YTHDC1 in m6A‑depend manner
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00:08
25.
CircMET
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00:01
26.
CircMET downregulates CDKN2A mRNA by direct binding
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01:34
27.
CircMET
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02:32
28.
CircMET downregulates CDKN2A mRNA by direct binding
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00:35
29.
CircMET downregulates CDKN2A mRNA by direct binding
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05:04
30.
CircMET accelerates the decay of CDKN2A mRNA by recruitment of YTHDF2
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01:04
31.
CircMET accelerates the decay of CDKN2A mRNA by recruitment of YTHDF2
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00:01
32.
Proliferation were inhibited by transfection with ΔYTHDF2 and gRNA-CDKN2A
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00:11
33.
Slide 20
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01:06
34.
CircMET functions as a ceRNA to sponge miR-1197
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00:27
35.
CircMET functions as a ceRNA to sponge miR-1197
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00:06
36.
CircMET functions as a ceRNA to sponge miR-1197
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00:48
37.
miR-1197 binds to 3’-UTR of SMAD3 mRNA
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00:03
38.
CircMET promotes SMAD3 expression through post‑transcriptional regulation
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00:51
39.
miR-1197 binds to 3’-UTR of SMAD3 mRNA
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00:56
40.
CircMET promotes SMAD3 expression through post‑transcriptional regulation
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00:01
41.
miR-1197 inhibits cell proliferation by downregulated SMAD3
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05:38
42.
Slide 27