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00:00
1.
index 1
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00:30
2.
Breast Cancer
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00:56
3.
Triple-Negative Breast Cancer(TNBC)
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01:29
4.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
02:06
5.
Circular RNA (CircRNA)
-
02:23
6.
Functions of circRNA
-
02:49
7.
MicroRNA (miRNA)
-
03:20
8.
Aim
-
04:01
9.
The expression and prognostic significance of circWAC in TNBC
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05:01
10.
Features of circWAC
-
06:14
11.
CircWAC was mainly distributed in the cytoplasm
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06:57
12.
CircWAC decrease chemosensitivity to PTX in TNBC
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07:35
13.
CircWAC decrease chemosensitivity to PTX in TNBC
-
08:19
14.
CircWAC decrease chemosensitivity to PTX in TNBC
-
09:31
15.
CircWAC acts as a sponge of miR-142 in TNBC
-
10:11
16.
CircWAC acts as a sponge of miR-142 in TNBC
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11:42
17.
CircWAC acts as a sponge of miR-142 in TNBC
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12:12
18.
CircWAC regulates PTX resistance by targeting miR-142
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13:16
19.
CircWAC regulates PTX resistance by targeting miR-142
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13:45
20.
WWP1 is the direct target gene of miR-142
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14:57
21.
WWP1 is the direct target gene of miR-142
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15:56
22.
WWP1 is the direct target gene of miR-142
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17:24
23.
The expression and prognostic significance of circWAC in TNBC
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17:54
24.
Inhibition of circWAC increases sensitivity to PTX in vivo
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19:17
25.
Conclusion
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19:51
26.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
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20:53
27.
Thank you for listening.
-
21:15
28.
Model for WWP1-mediated PTEN K27-linked polyubiquitination in tumor development and progression
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21:23
29.
PI3K/AKT pathway
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21:23
30.
Slide 29
-
21:27
31.
CircWAC had no obvious relationship with cell metastasis and invasion
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21:27
32.
Thank you for listening.
-
21:27
33.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
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21:28
34.
Conclusion
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21:28
35.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
21:29
36.
The expression and prognostic significance of circWAC in TNBC
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21:29
37.
WWP1 is the direct target gene of miR-142
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21:51
38.
WWP1 is the direct target gene of miR-142
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21:58
39.
WWP1 is the direct target gene of miR-142
-
23:55
40.
Model for WWP1-mediated PTEN K27-linked polyubiquitination in tumor development and progression
-
23:57
41.
PI3K/AKT pathway
-
23:58
42.
Slide 29
-
23:58
43.
CircWAC had no obvious relationship with cell metastasis and invasion
-
23:58
44.
Thank you for listening.
-
23:59
45.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
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23:59
46.
Conclusion
-
23:59
47.
Inhibition of circWAC increases sensitivity to PTX in vivo
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24:00
48.
The expression and prognostic significance of circWAC in TNBC
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24:00
49.
WWP1 is the direct target gene of miR-142
-
24:00
50.
WWP1 is the direct target gene of miR-142
-
24:01
51.
WWP1 is the direct target gene of miR-142
-
24:01
52.
CircWAC regulates PTX resistance by targeting miR-142
-
24:01
53.
CircWAC regulates PTX resistance by targeting miR-142
-
24:05
54.
CircWAC acts as a sponge of miR-142 in TNBC
-
24:05
55.
CircWAC acts as a sponge of miR-142 in TNBC
-
24:05
56.
CircWAC acts as a sponge of miR-142 in TNBC
-
24:06
57.
CircWAC decrease chemosensitivity to PTX in TNBC
-
24:39
58.
CircWAC decrease chemosensitivity to PTX in TNBC
-
24:40
59.
CircWAC decrease chemosensitivity to PTX in TNBC
-
24:40
60.
CircWAC was mainly distributed in the cytoplasm
-
24:40
61.
Features of circWAC
-
24:41
62.
The expression and prognostic significance of circWAC in TNBC
-
24:41
63.
Aim
-
24:42
64.
MicroRNA (miRNA)
-
24:42
65.
Functions of circRNA
-
24:42
66.
Circular RNA (CircRNA)
-
24:43
67.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
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24:43
68.
Triple-Negative Breast Cancer(TNBC)
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25:16
69.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
25:46
70.
Circular RNA (CircRNA)
-
25:48
71.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
25:56
72.
Circular RNA (CircRNA)
-
26:01
73.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
27:12
74.
Circular RNA (CircRNA)
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27:12
75.
Functions of circRNA
-
27:15
76.
Circular RNA (CircRNA)
-
27:17
77.
Functions of circRNA
-
27:17
78.
MicroRNA (miRNA)
-
27:25
79.
Functions of circRNA
-
27:46
80.
MicroRNA (miRNA)
-
27:47
81.
Aim
-
28:50
82.
The expression and prognostic significance of circWAC in TNBC
-
28:55
83.
Features of circWAC
-
28:56
84.
CircWAC was mainly distributed in the cytoplasm
-
28:56
85.
CircWAC decrease chemosensitivity to PTX in TNBC
-
28:56
86.
CircWAC was mainly distributed in the cytoplasm
-
28:58
87.
CircWAC decrease chemosensitivity to PTX in TNBC
-
29:19
88.
CircWAC was mainly distributed in the cytoplasm
-
29:20
89.
Features of circWAC
-
29:20
90.
The expression and prognostic significance of circWAC in TNBC
-
29:25
91.
Features of circWAC
-
29:54
92.
CircWAC was mainly distributed in the cytoplasm
-
30:45
93.
CircWAC decrease chemosensitivity to PTX in TNBC
-
30:45
94.
CircWAC decrease chemosensitivity to PTX in TNBC
-
30:46
95.
CircWAC decrease chemosensitivity to PTX in TNBC
-
31:00
96.
CircWAC acts as a sponge of miR-142 in TNBC
-
31:00
97.
CircWAC acts as a sponge of miR-142 in TNBC
-
31:01
98.
CircWAC acts as a sponge of miR-142 in TNBC
-
31:01
99.
CircWAC regulates PTX resistance by targeting miR-142
-
31:02
100.
CircWAC regulates PTX resistance by targeting miR-142
-
31:02
101.
WWP1 is the direct target gene of miR-142
-
31:03
102.
WWP1 is the direct target gene of miR-142
-
31:03
103.
WWP1 is the direct target gene of miR-142
-
31:05
104.
WWP1 is the direct target gene of miR-142
-
31:30
105.
WWP1 is the direct target gene of miR-142
-
31:39
106.
The expression and prognostic significance of circWAC in TNBC
-
31:40
107.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
31:41
108.
Conclusion
-
32:25
109.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
-
33:46
110.
Conclusion
-
33:46
111.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
33:46
112.
The expression and prognostic significance of circWAC in TNBC
-
33:47
113.
WWP1 is the direct target gene of miR-142
-
33:47
114.
WWP1 is the direct target gene of miR-142
-
33:47
115.
WWP1 is the direct target gene of miR-142
-
33:48
116.
CircWAC regulates PTX resistance by targeting miR-142
-
33:48
117.
CircWAC regulates PTX resistance by targeting miR-142
-
33:48
118.
CircWAC acts as a sponge of miR-142 in TNBC
-
33:49
119.
CircWAC acts as a sponge of miR-142 in TNBC
-
33:49
120.
CircWAC acts as a sponge of miR-142 in TNBC
-
33:49
121.
CircWAC decrease chemosensitivity to PTX in TNBC
-
33:50
122.
CircWAC decrease chemosensitivity to PTX in TNBC
-
33:50
123.
CircWAC decrease chemosensitivity to PTX in TNBC
-
33:50
124.
CircWAC was mainly distributed in the cytoplasm
-
33:51
125.
Features of circWAC
-
33:51
126.
The expression and prognostic significance of circWAC in TNBC
-
33:52
127.
Aim
-
33:52
128.
MicroRNA (miRNA)
-
33:52
129.
Functions of circRNA
-
33:53
130.
Circular RNA (CircRNA)
-
33:53
131.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
33:53
132.
Triple-Negative Breast Cancer(TNBC)
-
33:54
133.
Breast Cancer
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34:48
134.
Triple-Negative Breast Cancer(TNBC)
-
34:49
135.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
34:52
136.
Circular RNA (CircRNA)
-
34:55
137.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
34:55
138.
Triple-Negative Breast Cancer(TNBC)
-
35:00
139.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
35:25
140.
Triple-Negative Breast Cancer(TNBC)
-
35:34
141.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
35:35
142.
Circular RNA (CircRNA)
-
35:42
143.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
37:20
144.
Circular RNA (CircRNA)
-
37:20
145.
Functions of circRNA
-
37:22
146.
Circular RNA (CircRNA)
-
37:22
147.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
37:26
148.
Circular RNA (CircRNA)
-
37:27
149.
Functions of circRNA
-
37:29
150.
MicroRNA (miRNA)
-
37:30
151.
Functions of circRNA
-
37:42
152.
Circular RNA (CircRNA)
-
37:43
153.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
37:56
154.
Circular RNA (CircRNA)
-
37:57
155.
Functions of circRNA
-
37:57
156.
MicroRNA (miRNA)
-
37:58
157.
Aim
-
38:01
158.
MicroRNA (miRNA)
-
38:07
159.
Functions of circRNA
-
38:08
160.
Circular RNA (CircRNA)
-
38:08
161.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
39:03
162.
Triple-Negative Breast Cancer(TNBC)
-
40:37
163.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
40:44
164.
Circular RNA (CircRNA)
-
41:00
165.
Functions of circRNA
-
41:00
166.
MicroRNA (miRNA)
-
41:01
167.
Aim
-
42:19
168.
The expression and prognostic significance of circWAC in TNBC
-
42:28
169.
Features of circWAC
-
43:47
170.
CircWAC was mainly distributed in the cytoplasm
-
43:48
171.
CircWAC decrease chemosensitivity to PTX in TNBC
-
43:48
172.
CircWAC decrease chemosensitivity to PTX in TNBC
-
43:49
173.
CircWAC decrease chemosensitivity to PTX in TNBC
-
44:20
174.
CircWAC was mainly distributed in the cytoplasm
-
44:21
175.
CircWAC decrease chemosensitivity to PTX in TNBC
-
44:21
176.
CircWAC decrease chemosensitivity to PTX in TNBC
-
44:22
177.
CircWAC decrease chemosensitivity to PTX in TNBC
-
44:22
178.
CircWAC acts as a sponge of miR-142 in TNBC
-
44:22
179.
CircWAC acts as a sponge of miR-142 in TNBC
-
44:23
180.
CircWAC acts as a sponge of miR-142 in TNBC
-
44:23
181.
CircWAC regulates PTX resistance by targeting miR-142
-
44:23
182.
CircWAC regulates PTX resistance by targeting miR-142
-
44:24
183.
WWP1 is the direct target gene of miR-142
-
44:24
184.
WWP1 is the direct target gene of miR-142
-
44:24
185.
WWP1 is the direct target gene of miR-142
-
44:25
186.
The expression and prognostic significance of circWAC in TNBC
-
44:25
187.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
44:26
188.
Conclusion
-
44:26
189.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
-
45:20
190.
Conclusion
-
45:20
191.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
45:20
192.
The expression and prognostic significance of circWAC in TNBC
-
45:21
193.
WWP1 is the direct target gene of miR-142
-
45:21
194.
WWP1 is the direct target gene of miR-142
-
45:22
195.
WWP1 is the direct target gene of miR-142
-
45:22
196.
CircWAC regulates PTX resistance by targeting miR-142
-
45:22
197.
CircWAC regulates PTX resistance by targeting miR-142
-
45:23
198.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:23
199.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:23
200.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:24
201.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:29
202.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:32
203.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:34
204.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:37
205.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:56
206.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:56
207.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:57
208.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:57
209.
CircWAC decrease chemosensitivity to PTX in TNBC
-
45:58
210.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:59
211.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:59
212.
CircWAC acts as a sponge of miR-142 in TNBC
-
45:59
213.
CircWAC regulates PTX resistance by targeting miR-142
-
46:00
214.
CircWAC regulates PTX resistance by targeting miR-142
-
46:02
215.
CircWAC regulates PTX resistance by targeting miR-142
-
46:02
216.
CircWAC acts as a sponge of miR-142 in TNBC
-
46:03
217.
CircWAC acts as a sponge of miR-142 in TNBC
-
46:03
218.
CircWAC acts as a sponge of miR-142 in TNBC
-
46:03
219.
CircWAC decrease chemosensitivity to PTX in TNBC
-
46:33
220.
CircWAC decrease chemosensitivity to PTX in TNBC
-
46:34
221.
CircWAC decrease chemosensitivity to PTX in TNBC
-
46:34
222.
CircWAC was mainly distributed in the cytoplasm
-
46:35
223.
Features of circWAC
-
46:35
224.
The expression and prognostic significance of circWAC in TNBC
-
46:36
225.
Aim
-
46:37
226.
MicroRNA (miRNA)
-
46:49
227.
Functions of circRNA
-
46:50
228.
Circular RNA (CircRNA)
-
46:51
229.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
48:07
230.
Triple-Negative Breast Cancer(TNBC)
-
48:08
231.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
-
48:08
232.
Circular RNA (CircRNA)
-
49:36
233.
Functions of circRNA
-
49:37
234.
MicroRNA (miRNA)
-
49:38
235.
Aim
-
49:38
236.
The expression and prognostic significance of circWAC in TNBC
-
49:39
237.
Features of circWAC
-
49:39
238.
CircWAC was mainly distributed in the cytoplasm
-
49:39
239.
CircWAC decrease chemosensitivity to PTX in TNBC
-
49:40
240.
CircWAC decrease chemosensitivity to PTX in TNBC
-
49:40
241.
CircWAC decrease chemosensitivity to PTX in TNBC
-
49:40
242.
CircWAC acts as a sponge of miR-142 in TNBC
-
49:41
243.
CircWAC acts as a sponge of miR-142 in TNBC
-
49:41
244.
CircWAC acts as a sponge of miR-142 in TNBC
-
49:41
245.
CircWAC regulates PTX resistance by targeting miR-142
-
49:42
246.
CircWAC regulates PTX resistance by targeting miR-142
-
49:42
247.
WWP1 is the direct target gene of miR-142
-
49:42
248.
WWP1 is the direct target gene of miR-142
-
49:43
249.
WWP1 is the direct target gene of miR-142
-
49:43
250.
The expression and prognostic significance of circWAC in TNBC
-
49:44
251.
Inhibition of circWAC increases sensitivity to PTX in vivo
-
49:45
252.
Conclusion
-
49:45
253.
Pros: They clearly discovered the network between circWAC and miR-142 using tissue samples from TNBC patients and databases. This research included an in vivo experiment to demonstrate how circWAC inhibition can improve chemosensitivity to PTX.They discov
-
56:02
254.
** after 20221101 林俐妤seminar.pptx