20221024 lab meeting_俐妤 | 賴亮全實驗室

Index

00:00 1.
index 1
00:02 2.
Slide 1
00:30 3.
index 2
00:58 4.
Breast Cancer
01:40 5.
Triple-Negative Breast Cancer(TNBC)
02:26 6.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
03:05 7.
MicroRNA (miRNA)
03:52 8.
Circular RNA (CircRNA)
03:56 9.
MicroRNA (miRNA)
04:21 10.
Circular RNA (CircRNA)
05:00 11.
Functions of circRNA
05:38 12.
PI3K/AKT pathway
07:04 13.
The expression and prognostic significance of circWAC in TNBC
15:51 14.
Features of circWAC
32:28 15.
CircWAC was mainly distributed in the cytoplasm
37:56 16.
CircWAC decrease chemosensitivity to PTX in TNBC
37:57 17.
CircWAC was mainly distributed in the cytoplasm
38:15 18.
CircWAC decrease chemosensitivity to PTX in TNBC
38:18 19.
CircWAC was mainly distributed in the cytoplasm
39:20 20.
CircWAC decrease chemosensitivity to PTX in TNBC
44:15 21.
CircWAC decrease chemosensitivity to PTX in TNBC
45:31 22.
CircWAC decrease chemosensitivity to PTX in TNBC
54:14 23.
CircWAC acts as a sponge of miR-142 in TNBC
54:15 24.
CircWAC decrease chemosensitivity to PTX in TNBC
55:36 25.
CircWAC acts as a sponge of miR-142 in TNBC
56:41 26.
CircWAC acts as a sponge of miR-142 in TNBC
56:44 27.
CircWAC acts as a sponge of miR-142 in TNBC
57:14 28.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:23 29.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:24 30.
CircWAC acts as a sponge of miR-142 in TNBC
1:11:26 31.
CircWAC acts as a sponge of miR-142 in TNBC
1:13:34 32.
CircWAC regulates PTX resistance by targeting miR-142
1:19:54 33.
CircWAC regulates PTX resistance by targeting miR-142
1:21:13 34.
WWP1 is the direct target gene of miR-142
1:25:20 35.
WWP1 is the direct target gene of miR-142
1:25:55 36.
WWP1 is the direct target gene of miR-142
1:29:55 37.
The expression and prognostic significance of circWAC in TNBC
1:30:41 38.
Inhibition of circWAC increases sensitivity to PTX in vivo
1:39:58 39.
Conclusion
1:43:26 40.
Inhibition of circWAC increases sensitivity to PTX in vivo

Notes (0)

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Comment

00:00 1.
index 1
00:02 2.
Slide 1
00:30 3.
index 2
00:58 4.
Breast Cancer
01:40 5.
Triple-Negative Breast Cancer(TNBC)
02:26 6.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
03:05 7.
MicroRNA (miRNA)
03:52 8.
Circular RNA (CircRNA)
03:56 9.
MicroRNA (miRNA)
04:21 10.
Circular RNA (CircRNA)
05:00 11.
Functions of circRNA
05:38 12.
PI3K/AKT pathway
07:04 13.
The expression and prognostic significance of circWAC in TNBC
15:51 14.
Features of circWAC
32:28 15.
CircWAC was mainly distributed in the cytoplasm
37:56 16.
CircWAC decrease chemosensitivity to PTX in TNBC
37:57 17.
CircWAC was mainly distributed in the cytoplasm
38:15 18.
CircWAC decrease chemosensitivity to PTX in TNBC
38:18 19.
CircWAC was mainly distributed in the cytoplasm
39:20 20.
CircWAC decrease chemosensitivity to PTX in TNBC
44:15 21.
CircWAC decrease chemosensitivity to PTX in TNBC
45:31 22.
CircWAC decrease chemosensitivity to PTX in TNBC
54:14 23.
CircWAC acts as a sponge of miR-142 in TNBC
54:15 24.
CircWAC decrease chemosensitivity to PTX in TNBC
55:36 25.
CircWAC acts as a sponge of miR-142 in TNBC
56:41 26.
CircWAC acts as a sponge of miR-142 in TNBC
56:44 27.
CircWAC acts as a sponge of miR-142 in TNBC
57:14 28.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:23 29.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:24 30.
CircWAC acts as a sponge of miR-142 in TNBC
1:11:26 31.
CircWAC acts as a sponge of miR-142 in TNBC
1:13:34 32.
CircWAC regulates PTX resistance by targeting miR-142
1:19:54 33.
CircWAC regulates PTX resistance by targeting miR-142
1:21:13 34.
WWP1 is the direct target gene of miR-142
1:25:20 35.
WWP1 is the direct target gene of miR-142
1:25:55 36.
WWP1 is the direct target gene of miR-142
1:29:55 37.
The expression and prognostic significance of circWAC in TNBC
1:30:41 38.
Inhibition of circWAC increases sensitivity to PTX in vivo
1:39:58 39.
Conclusion
1:43:26 40.
Inhibition of circWAC increases sensitivity to PTX in vivo

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20221024 lab meeting_俐妤

Duration: 1:46:50, Browse: 306, Last Updated: 2022-10-24

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00:00 1.
index 1
00:02 2.
Slide 1
00:30 3.
index 2
00:58 4.
Breast Cancer
01:40 5.
Triple-Negative Breast Cancer(TNBC)
02:26 6.
Paclitaxel(PTX) is frequently used as the first-line treatment drug in BC.Chemoresistance is a major problem of cancer treatment associated with poor response.Mechanism of action of PTX
03:05 7.
MicroRNA (miRNA)
03:52 8.
Circular RNA (CircRNA)
03:56 9.
MicroRNA (miRNA)
04:21 10.
Circular RNA (CircRNA)
05:00 11.
Functions of circRNA
05:38 12.
PI3K/AKT pathway
07:04 13.
The expression and prognostic significance of circWAC in TNBC
15:51 14.
Features of circWAC
32:28 15.
CircWAC was mainly distributed in the cytoplasm
37:56 16.
CircWAC decrease chemosensitivity to PTX in TNBC
37:57 17.
CircWAC was mainly distributed in the cytoplasm
38:15 18.
CircWAC decrease chemosensitivity to PTX in TNBC
38:18 19.
CircWAC was mainly distributed in the cytoplasm
39:20 20.
CircWAC decrease chemosensitivity to PTX in TNBC
44:15 21.
CircWAC decrease chemosensitivity to PTX in TNBC
45:31 22.
CircWAC decrease chemosensitivity to PTX in TNBC
54:14 23.
CircWAC acts as a sponge of miR-142 in TNBC
54:15 24.
CircWAC decrease chemosensitivity to PTX in TNBC
55:36 25.
CircWAC acts as a sponge of miR-142 in TNBC
56:41 26.
CircWAC acts as a sponge of miR-142 in TNBC
56:44 27.
CircWAC acts as a sponge of miR-142 in TNBC
57:14 28.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:23 29.
CircWAC acts as a sponge of miR-142 in TNBC
1:01:24 30.
CircWAC acts as a sponge of miR-142 in TNBC
1:11:26 31.
CircWAC acts as a sponge of miR-142 in TNBC
1:13:34 32.
CircWAC regulates PTX resistance by targeting miR-142
1:19:54 33.
CircWAC regulates PTX resistance by targeting miR-142
1:21:13 34.
WWP1 is the direct target gene of miR-142
1:25:20 35.
WWP1 is the direct target gene of miR-142
1:25:55 36.
WWP1 is the direct target gene of miR-142
1:29:55 37.
The expression and prognostic significance of circWAC in TNBC
1:30:41 38.
Inhibition of circWAC increases sensitivity to PTX in vivo
1:39:58 39.
Conclusion
1:43:26 40.
Inhibition of circWAC increases sensitivity to PTX in vivo

Location

Folder name

2022

Author

林俐妤

Branch

賴亮全教授

Created

2022-10-24 11:10:15

Last Updated

2022-10-24 11:40:33

Duration

1:46:50