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00:00
1.
index 1
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00:32
2.
Cyclin E1 and CDK4/6
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00:32
3.
Palbociclib , CDK4/6 inhibitor
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00:32
4.
Cyclin E1 and CDK4/6
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00:33
5.
Slide 1
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00:33
6.
Cyclin E1 and CDK4/6
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01:19
7.
Palbociclib , CDK4/6 inhibitor
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01:22
8.
Cyclin E1 and CDK4/6
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04:27
9.
Palbociclib , CDK4/6 inhibitor
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05:50
10.
Cyclin E1 and CDK4/6
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05:58
11.
Palbociclib , CDK4/6 inhibitor
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07:14
12.
Cyclin E1 dysregulation promotes CDK4/6 inhibitor resistance
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07:16
13.
Palbociclib , CDK4/6 inhibitor
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09:44
14.
Cyclin E1 dysregulation promotes CDK4/6 inhibitor resistance
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09:57
15.
Palbociclib , CDK4/6 inhibitor
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10:25
16.
Cyclin E1 dysregulation promotes CDK4/6 inhibitor resistance
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15:20
17.
Cyclin E1 dysregulation promotes CDK4/6 inhibitor resistance
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28:48
18.
EILA predicts poor prognosis in breast cancer patients
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40:12
19.
EILA predicts poor prognosis in breast cancer patients
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51:41
20.
EILA is required for CDK4/6 inhibitor resistance
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54:11
21.
Cellular Senescence Detection Kit - SPiDER-βGal
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54:12
22.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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54:16
23.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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54:19
24.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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54:19
25.
Cellular Senescence Detection Kit - SPiDER-βGal
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54:19
26.
EILA is required for CDK4/6 inhibitor resistance
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54:20
27.
EILA predicts poor prognosis in breast cancer patients
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54:21
28.
EILA predicts poor prognosis in breast cancer patients
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54:21
29.
EILA predicts poor prognosis in breast cancer patients
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54:22
30.
EILA is required for CDK4/6 inhibitor resistance
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1:00:54
31.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:01:47
32.
EILA is required for CDK4/6 inhibitor resistance
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1:02:13
33.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:14
34.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:02:24
35.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:25
36.
EILA is required for CDK4/6 inhibitor resistance
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1:02:27
37.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:28
38.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:02:30
39.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:30
40.
EILA is required for CDK4/6 inhibitor resistance
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1:02:31
41.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:32
42.
EILA is required for CDK4/6 inhibitor resistance
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1:02:33
43.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:34
44.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:02:36
45.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:36
46.
EILA is required for CDK4/6 inhibitor resistance
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1:02:43
47.
Cellular Senescence Detection Kit - SPiDER-βGal
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1:02:44
48.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:02:48
49.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:02:49
50.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:05:14
51.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:11:46
52.
EILA hinders the ubiquitination-mediated degradation of cyclin E1
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1:11:49
53.
Hairpin A of EILA stabilizes cyclin E1 protein by its C-terminal domain
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1:12:03
54.
EILA hinders the ubiquitination-mediated degradation of cyclin E1
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1:15:14
55.
EILA hinders the ubiquitination-mediated degradation of cyclin E1
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1:18:05
56.
EILA expression is regulated by CTCF/CDK8/TFII-I complexes
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1:22:36
57.
EILA expression is regulated by CTCF/CDK8/TFII-I complexes
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1:26:05
58.
EILA promotes CDK4/6 inhibitor resistance in vivo
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1:27:10
59.
EILA promotes CDK4/6 inhibitor resistance in vivo
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1:28:15
60.
EILA predicts poor response to CDK4/6i treatment
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1:29:27
61.
Slide 19
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1:29:28
62.
EILA predicts poor response to CDK4/6i treatment