20240226 lab meeting_楷軒 | 賴亮全實驗室

索引

00:00 1.
index 1
00:23 2.
Colorectal cancer
01:01 3.
Colorectal cancer low survival rate in stage 4
01:33 4.
Hypoxia in cancer
02:22 5.
CircRNA
03:23 6.
CircINSIG1 is upregulated by hypoxia in CRC
05:23 7.
Characterization of hypoxia-induced circINSIG1 in CRC
08:14 8.
High expression of circINSIG1 lower survival rate
10:56 9.
CircINSIG1 had protein coding potential in circRNADb prediction
11:02 10.
High expression of circINSIG1 lower survival rate
11:59 11.
CircINSIG1 had protein coding potential in circRNADb prediction
27:31 12.
CircINSIG1-121 were verified with specific amino acids
30:00 13.
CircINSIG1 had protein coding potential in circRNADb prediction
30:11 14.
CircINSIG1-121 were verified with specific amino acids
32:46 15.
High expression of circINSIG1-121 in CRC tumor tissue
33:41 16.
High expression of circINSIG1-121 lower survival rate
35:20 17.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
38:56 18.
CircINSIG1-121 promoted CRC progression
40:22 19.
CRC growth and metastasis were induced by circINSIG1-121
41:22 20.
CircINSIG1-121 downregulated INSIG1 protein expression
41:50 21.
CRC growth and metastasis were induced by circINSIG1-121
41:51 22.
CircINSIG1-121 promoted CRC progression
41:52 23.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
41:56 24.
CircINSIG1-121 promoted CRC progression
41:56 25.
CRC growth and metastasis were induced by circINSIG1-121
41:57 26.
CircINSIG1-121 downregulated INSIG1 protein expression
42:40 27.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
42:53 28.
CircINSIG1-121 downregulated INSIG1 protein expression
44:05 29.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
51:46 30.
SREBP2 target genes were induced by circINSIG1-121
51:54 31.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
52:00 32.
SREBP2 target genes were induced by circINSIG1-121
52:23 33.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
52:49 34.
** after 20240226 meeting.pptx
52:56 35.
ubiquitination
54:11 36.
** after 20240226 meeting.pptx
54:22 37.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
54:23 38.
** after 20240226 meeting.pptx
54:28 39.
ubiquitination
54:47 40.
** after 20240226 meeting.pptx
54:55 41.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
57:54 42.
INSIG1 were ubiquitinated on K156/158 by ASB6-CUL5
1:04:00 43.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:06:01 44.
** after 20240226 meeting.pptx
1:06:09 45.
INSIG1 and SCAP
1:07:10 46.
** after 20240226 meeting.pptx
1:07:23 47.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:07:27 48.
EIF4A3 interacted with circINSIG1 downstream through hypoxia
1:09:39 49.
EIF4A3 promoted circINSIG1 circulation by circINSIG1 downstream 1-6
1:13:26 50.
SREBP2 target genes were induced by EIF4A3
1:13:49 51.
CircINSIG1 induced PDX CRC progression
1:15:40 52.
CircINSIG1 induced SREBP2 target genes and cholesterol metabolism
1:16:04 53.
Conclusion
1:17:11 54.
Pros
1:17:46 55.
Slide 29
1:17:51 56.
Pros
1:17:52 57.
Conclusion

筆記 (0)

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討論

00:00 1.
index 1
00:23 2.
Colorectal cancer
01:01 3.
Colorectal cancer low survival rate in stage 4
01:33 4.
Hypoxia in cancer
02:22 5.
CircRNA
03:23 6.
CircINSIG1 is upregulated by hypoxia in CRC
05:23 7.
Characterization of hypoxia-induced circINSIG1 in CRC
08:14 8.
High expression of circINSIG1 lower survival rate
10:56 9.
CircINSIG1 had protein coding potential in circRNADb prediction
11:02 10.
High expression of circINSIG1 lower survival rate
11:59 11.
CircINSIG1 had protein coding potential in circRNADb prediction
27:31 12.
CircINSIG1-121 were verified with specific amino acids
30:00 13.
CircINSIG1 had protein coding potential in circRNADb prediction
30:11 14.
CircINSIG1-121 were verified with specific amino acids
32:46 15.
High expression of circINSIG1-121 in CRC tumor tissue
33:41 16.
High expression of circINSIG1-121 lower survival rate
35:20 17.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
38:56 18.
CircINSIG1-121 promoted CRC progression
40:22 19.
CRC growth and metastasis were induced by circINSIG1-121
41:22 20.
CircINSIG1-121 downregulated INSIG1 protein expression
41:50 21.
CRC growth and metastasis were induced by circINSIG1-121
41:51 22.
CircINSIG1-121 promoted CRC progression
41:52 23.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
41:56 24.
CircINSIG1-121 promoted CRC progression
41:56 25.
CRC growth and metastasis were induced by circINSIG1-121
41:57 26.
CircINSIG1-121 downregulated INSIG1 protein expression
42:40 27.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
42:53 28.
CircINSIG1-121 downregulated INSIG1 protein expression
44:05 29.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
51:46 30.
SREBP2 target genes were induced by circINSIG1-121
51:54 31.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
52:00 32.
SREBP2 target genes were induced by circINSIG1-121
52:23 33.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
52:49 34.
** after 20240226 meeting.pptx
52:56 35.
ubiquitination
54:11 36.
** after 20240226 meeting.pptx
54:22 37.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
54:23 38.
** after 20240226 meeting.pptx
54:28 39.
ubiquitination
54:47 40.
** after 20240226 meeting.pptx
54:55 41.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
57:54 42.
INSIG1 were ubiquitinated on K156/158 by ASB6-CUL5
1:04:00 43.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:06:01 44.
** after 20240226 meeting.pptx
1:06:09 45.
INSIG1 and SCAP
1:07:10 46.
** after 20240226 meeting.pptx
1:07:23 47.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:07:27 48.
EIF4A3 interacted with circINSIG1 downstream through hypoxia
1:09:39 49.
EIF4A3 promoted circINSIG1 circulation by circINSIG1 downstream 1-6
1:13:26 50.
SREBP2 target genes were induced by EIF4A3
1:13:49 51.
CircINSIG1 induced PDX CRC progression
1:15:40 52.
CircINSIG1 induced SREBP2 target genes and cholesterol metabolism
1:16:04 53.
Conclusion
1:17:11 54.
Pros
1:17:46 55.
Slide 29
1:17:51 56.
Pros
1:17:52 57.
Conclusion

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索引
筆記
討論
全螢幕

20240226 lab meeting_楷軒

長度: 1:18:21, 瀏覽: 63, 最近修訂: 2024-02-26

00:00 1.
index 1
00:23 2.
Colorectal cancer
01:01 3.
Colorectal cancer low survival rate in stage 4
01:33 4.
Hypoxia in cancer
02:22 5.
CircRNA
03:23 6.
CircINSIG1 is upregulated by hypoxia in CRC
05:23 7.
Characterization of hypoxia-induced circINSIG1 in CRC
08:14 8.
High expression of circINSIG1 lower survival rate
10:56 9.
CircINSIG1 had protein coding potential in circRNADb prediction
11:02 10.
High expression of circINSIG1 lower survival rate
11:59 11.
CircINSIG1 had protein coding potential in circRNADb prediction
27:31 12.
CircINSIG1-121 were verified with specific amino acids
30:00 13.
CircINSIG1 had protein coding potential in circRNADb prediction
30:11 14.
CircINSIG1-121 were verified with specific amino acids
32:46 15.
High expression of circINSIG1-121 in CRC tumor tissue
33:41 16.
High expression of circINSIG1-121 lower survival rate
35:20 17.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
38:56 18.
CircINSIG1-121 promoted CRC progression
40:22 19.
CRC growth and metastasis were induced by circINSIG1-121
41:22 20.
CircINSIG1-121 downregulated INSIG1 protein expression
41:50 21.
CRC growth and metastasis were induced by circINSIG1-121
41:51 22.
CircINSIG1-121 promoted CRC progression
41:52 23.
CircINSIG1-121 promoted CRC growth in both HCT8 and DLD1
41:56 24.
CircINSIG1-121 promoted CRC progression
41:56 25.
CRC growth and metastasis were induced by circINSIG1-121
41:57 26.
CircINSIG1-121 downregulated INSIG1 protein expression
42:40 27.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
42:53 28.
CircINSIG1-121 downregulated INSIG1 protein expression
44:05 29.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
51:46 30.
SREBP2 target genes were induced by circINSIG1-121
51:54 31.
CircINSIG1-121 induced cholesterol metabolism by INSIG1 ubiquitination
52:00 32.
SREBP2 target genes were induced by circINSIG1-121
52:23 33.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
52:49 34.
** after 20240226 meeting.pptx
52:56 35.
ubiquitination
54:11 36.
** after 20240226 meeting.pptx
54:22 37.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
54:23 38.
** after 20240226 meeting.pptx
54:28 39.
ubiquitination
54:47 40.
** after 20240226 meeting.pptx
54:55 41.
INSIG1 were K48 ubiquitinated on K156/158 sites by circINSIG1-121
57:54 42.
INSIG1 were ubiquitinated on K156/158 by ASB6-CUL5
1:04:00 43.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:06:01 44.
** after 20240226 meeting.pptx
1:06:09 45.
INSIG1 and SCAP
1:07:10 46.
** after 20240226 meeting.pptx
1:07:23 47.
ASB6 regulated INSIG1 stability and cholesterol metabolism in CRC
1:07:27 48.
EIF4A3 interacted with circINSIG1 downstream through hypoxia
1:09:39 49.
EIF4A3 promoted circINSIG1 circulation by circINSIG1 downstream 1-6
1:13:26 50.
SREBP2 target genes were induced by EIF4A3
1:13:49 51.
CircINSIG1 induced PDX CRC progression
1:15:40 52.
CircINSIG1 induced SREBP2 target genes and cholesterol metabolism
1:16:04 53.
Conclusion
1:17:11 54.
Pros
1:17:46 55.
Slide 29
1:17:51 56.
Pros
1:17:52 57.
Conclusion

位置

資料夾名稱

2024

發表人

朱庭汶

單位

賴亮全教授

建立

2024-02-26 14:31:38

最近修訂

2024-02-26 15:00:29

長度

1:18:21