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00:00
1.
index 1
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00:11
2.
為什麼要學呼吸生理學?不知道這個也活得好好的
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00:28
3.
何時需刻意地增加呼吸效率?
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01:50
4.
Outline
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01:58
4.1
Background
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03:04
4.2
Background
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05:04
4.3
除了氣體交換(吸氧排二氧化碳)外, 呼吸系統還有那些功能?
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05:22
4.4
Functions of Respiratory Sys.
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07:43
4.5
Overview
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09:42
5.
Outline
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09:48
5.1
Structure of Respiratory Sys.
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10:05
5.2
Structure of Respiratory Sys.
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10:36
5.3
Function of Nasal Passage
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11:51
5.4
Comparison of Airway Structure
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12:37
5.5
Airways of a Human Lung
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13:27
5.6
Main Airway Branches & Zones
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14:26
5.7
Main Airway Branches & Zones
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15:02
5.8
Alveoli
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16:00
5.9
The Human Lung
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16:44
5.10
Blood Supply of Lungs
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18:48
5.11
Respiratory Muscles_inspiration
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20:47
5.12
Respiratory Muscles_expiration
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23:45
5.13
那種呼吸比較有效率?為什麼?
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25:38
5.14
Pleural layers
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26:36
5.15
Cross Section of the Thoracic Cavity
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26:48
5.16
Intrapleural Space
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28:19
5.17
Pneumothorax
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29:31
6.
Outline
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29:37
6.1
Instrument for Measuring Lung Vol.
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33:11
6.2
Spirometer, Lung Volumes and Capacities
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36:51
6.3
Lung Volumes and Capacities
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38:31
6.4
什麼時候正常吐氣結束?
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39:12
6.5
Functional Residual Capacity
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41:31
6.6
Measurement of FRC
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41:32
6.7
Functional Residual Capacity
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42:53
6.8
Measurement of FRC
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43:48
6.9
Measurement of FRC
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46:57
7.
Overview
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47:04
7.1
Ventilation (通氣量)
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49:30
7.2
Dead Space (死腔)
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51:29
7.3
Fowler’s Method:Single-Breath Nitrogen Washout
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56:03
7.4
Bohr’s Method:Conservation of Mass
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59:58
7.5
Dalton’s Law
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1:02:40
7.6
Bohr’s Method (2)
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1:03:55
7.7
Alveolar Ventilation
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1:06:22
7.8
Alveolar Ventilation
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1:07:43
7.9
Uneven Ventilation inUpright Position
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1:08:32
7.10
Cause of the Regional Differences of Ventilation
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1:11:20
7.11
Closing Volume
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1:15:20
7.12
Closing Volume
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1:15:56
7.13
Partial Pressures of Gases in Various Parts
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1:16:47
7.14
O2 and CO2 Concentrations in Exhaled Gas
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1:18:07
7.15
Overview of Po2 and Pco2
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1:21:09
7.16
改變呼吸方式可改變那種氣體的分壓?
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1:21:31
7.17
Hyper-, Hypo-ventilation & Hyperpnea
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1:24:01
7.18
跑步後很喘,如何快速回到正常的呼吸速率?
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1:24:43
7.19
Hyperpnea
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1:28:31
7.20
How to measure PAO2?
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1:28:42
7.21
Alveolar Gas Equation
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1:30:21
7.22
Respiratory Quotient (呼吸商)
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1:32:35
7.23
Alveolar Gas Equation
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1:33:25
7.24
Reasons to Understand the Alveolar Gas Equation
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1:34:13
7.25
Case Study
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1:37:07
8.
Outline
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1:37:13
9.
Overview
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1:37:20
9.1
Perfusion (灌流量)
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1:38:10
9.2
Shunt (分流)
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1:41:49
9.3
Shunt Equation
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1:43:38
9.4
Uneven Perfusion in Upright Position
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1:44:17
9.5
Zone Model
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1:46:26
9.6
Hypoxic Pulmonary Vasoconstriction
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1:48:29
10.
Overview
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1:48:44
10.1
Matching of Ventilation & Perfusion
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1:49:56
10.2
Mis-matching of Ventilation & Perfusion
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1:50:26
10.3
V/Q受什麼影響?
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1:50:30
10.4
Matching of Ventilation & Perfusion
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1:52:27
10.5
Distribution of V and Q Within the Lung in the Upright Position
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1:54:20
10.6
Distribution of V /Q Ratio
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1:56:58
10.7
V/Q如何影響氣體的分壓?
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1:57:06
10.8
Effects of V /Q Ratio on PAo2 & PAco2
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1:58:51
10.9
Effects of V /Q Ratio on PAo2 & PAco2
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1:59:25
10.10
V /Q v.s. Po2 & Pco2
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2:02:46
10.11
V /Q Inequality of Normal Lung in the Upright Position
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2:07:32
10.12
Riley’s Three Compartment Model
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2:09:34
10.13
Riley’s Three Compartment Model
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2:11:42
10.14
Gas Exchange Computer Lab
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2:12:52
11.
Outline
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2:13:00
11.1
Key Points
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2:13:09
11.2
General Concepts and Terminology
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2:16:35
11.3
General Concepts and Terminology
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2:18:36
11.4
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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2:23:19
11.5
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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2:24:29
12.
Key Points
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2:24:37
12.1
Static Mechanical Properties
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2:26:47
12.2
Compliance Changes in Different Diseases
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2:28:24
12.3
Calculation of Compliance of Lung
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2:30:35
13.
Key Points
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2:30:39
13.1
Resistance
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2:31:49
13.2
The Airway Resistance
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2:32:42
13.3
The Airway Resistance
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2:35:04
13.4
The Airway Resistance
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2:38:05
13.5
The Airway Resistance
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2:39:16
13.6
Calculation of Dynamic Resistance
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2:40:26
13.7
Evaluation of Airway Resistance
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2:44:09
13.8
Evaluation of Abnormality in Lung Vol.
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2:46:31
13.9
Flow-volume Curves
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2:47:52
13.10
Isovolume Pressure-flow Curves
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2:50:07
13.11
Flow-Volume Relationship
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2:50:55
13.12
Dynamic Airway Compression
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2:59:11
13.13
EPP is Influenced by Lung Elastic Recoil
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3:01:26
13.14
Pursed Lip Breathing (噘嘴吐氣)
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3:03:50
13.15
Abnormality in Lung Vol.
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3:04:21
13.16
Interpretation of Flow-Vol Loop
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3:05:16
13.17
Obstructive Lung Vol. Defect
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3:05:57
13.18
Chronic Obstructive Pulmonary Disease (慢性阻塞性肺病; COPD)
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3:06:27
13.19
Emphysema (肺氣腫)
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3:06:46
13.20
Asthma (氣喘)
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3:07:47
13.21
吸煙豬肺影片
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3:10:19
13.22
Restrictive Lung Vol. Defect
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3:11:13
13.23
Examples of Restrictive Lung Dz.
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3:11:47
13.24
做那些動作使呼吸效率增加?為什麼?
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3:14:01
14.
Key Points
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3:14:07
14.1
Hysteresis
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3:16:19
14.2
Surface Tension
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3:17:44
14.3
Law of LaPlace
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3:19:13
14.4
Surfactants
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3:19:27
14.5
Importance of Lung Surfactant
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3:20:25
14.6
Work of Breathing
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3:21:14
14.7
Effects of Diseases on PV Curve
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3:22:58
14.8
為什麼肺氣腫的病人每次的呼吸都很吃力?
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3:23:24
14.9
Effects of Diseases on PV Curve
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3:24:38
15.
Key Points
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3:24:45
15.1
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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3:25:25
15.2
Elastic Recoil of the Chest Wall
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3:26:49
15.3
Elastic Recoil of the Chest Wall
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3:28:56
15.4
Lung-Chest Wall Couplingin Static Status at Different Lung Volume
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3:29:38
15.5
Lung-chest Wall Coupling to Determine FRC
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3:32:50
15.6
Static Elastic Properties of the Lung and Chest Wall
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3:34:50
15.7
Static Elastic Properties of the Lung and Chest Wall
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3:36:31
15.8
Transmural Pressure Across the Lung Wall in Dynamic Status
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3:37:15
15.9
The Mechanics of Quiet Breathing
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3:41:41
15.10
P-V Relationships and Schematic Events of Resp. Cycle
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3:46:16
15.11
P-V Relationships and Schematic Events of Resp. Cycle
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3:47:21
16.
Outline
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3:47:41
17.
Overview
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3:47:45
17.1
Diffusion and Gas Transport
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3:47:55
17.2
Alveolo-Capillary Barrier
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3:48:18
17.3
Diffusion
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3:49:09
17.4
Diffusion Capacity
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3:51:14
17.5
Diffusion Capacity
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3:52:39
17.6
Physiologic Changes That Alter Diffusion Capacity
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3:53:51
17.7
Capillary Transit Time
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3:55:59
17.8
Perfusion-limited Gas
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3:57:20
17.9
Diffusion-limited Gas
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3:58:02
17.10
Diffusion and Perfusion Limitations
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4:00:49
17.11
Interpretation of Pulmonary Function Test
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4:04:28
18.
Transport of O2 and CO2
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4:04:33
19.
Oxygen Transport
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4:05:09
19.1
Blood Gas Measurement
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4:07:05
19.2
Hemoglobin
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4:07:27
19.3
O2 Bound to Hb
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4:08:51
19.4
What does pulse oximeter measure?O2 dissolved in the blood plasmaO2 bound with hemoglobin
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4:09:32
19.5
What does pulse oximeter measure?O2 dissolved in the blood plasmaO2 bound with hemoglobin
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4:10:42
19.6
Cooperative Interactions
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4:12:38
19.7
O2 Bound to Hb
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4:16:44
19.8
O2 Bound to Hb
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4:19:10
19.9
Factors Affecting O2 Bound to Hb
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4:21:04
20.
CO2 Transport
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4:21:47
20.1
CO2 Transport
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4:23:26
20.2
CO2 Transport
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4:23:57
20.3
CO2 Equilibrium Curve
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4:27:05
21.
Assessment of Arterial Hypoxemia
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4:29:50
21.1
Questions
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4:32:59
22.
Outline
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4:33:09
22.1
Control of Respiration
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4:34:11
22.2
Overview
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4:34:33
22.3
Receptors
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4:35:26
22.4
Receptors
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4:37:22
22.5
Receptors
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4:38:30
22.6
Central Controller in Brain Stem
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4:38:45
22.7
你覺得吸氣比較重要還是呼氣比較重要?
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4:38:54
22.8
Central Controller
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4:39:38
22.9
Central Controller
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4:41:45
22.10
Respiratory Neurons in the Brain Stem
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4:45:28
22.11
正常情況下,什麼時候正常呼吸的型態會改變?
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4:45:41
22.12
Central Controller
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4:46:24
22.13
Central Controller
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4:47:15
22.14
Effectors
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4:47:47
23.
Outline
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4:47:53
24.
Overview
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4:48:04
24.1
你覺得吸氧氣比較重要還是排二氧化碳比較重要?
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4:48:10
24.2
Chemical Control of Resp.
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4:49:12
24.3
Central Chemoreceptor
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4:50:17
24.4
Peripheral Chemoreceptor
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4:51:08
24.5
Regulation of breathing in response to changes in blood PCO2, PO2, and pH (H+) via negative feedback control
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4:53:11
25.
Outline
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4:53:15
25.1
Acid-base Balance
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4:54:49
25.2
Effectiveness of a Buffer System
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4:56:21
25.3
Bicarbonate
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4:56:53
25.4
The Effect of Bicarbonate on Blood pH
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4:58:23
25.5
Davenport Diagram
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4:59:49
25.6
Respiratory Disturbances
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5:00:42
25.7
Metabolic Disturbances
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5:01:16
25.8
Compensatory Responses
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5:03:36
25.9
Compensatory Responses
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5:04:10
26.
Outline
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5:04:26
26.1
Rest-to-Work Transitions
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5:05:21
26.2
Sub-maximal Exercise
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5:05:57
26.3
Ventilatory Control During Submaximal Exercise
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5:06:37
26.4
High Intensity Exercise
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5:07:28
26.5
High Intensity Exercise
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5:08:34
26.6
Oxygen Debt
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5:10:02
26.7
呼吸系統是運動的限制因子嗎?
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5:10:12
26.8
Do the Lungs Limit Exercise Performance?
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5:10:57
26.9
Effect of Training on Ventilation
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5:11:43
27.
How to Increase Resp. Function During Exercise?
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5:15:32
27.1
How to Increase Resp. Function During Exercise?
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5:19:15
28.
Effect of High Altitude on Resp. Function
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5:20:01
28.1
Immediate: Increased in Ventilation
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5:23:02
28.2
Days: Decreased Affinity of Hemoglobin for Oxygen
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5:24:40
28.3
Days to weeks: Increased Hemoglobin Production
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5:26:18
28.4
Respiratory Adaptations to High Altitude
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5:27:44
29.
Overview