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00:00
1.
Respiratory Physiology
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00:18
2.
請同學先進入Slido
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00:27
3.
為什麼要學呼吸生理學?不知道這個也活得好好的
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00:44
4.
何時需刻意地增加呼吸效率?
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01:14
5.
何時需刻意地增加呼吸效率?
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02:01
6.
Outline
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02:08
7.
Background
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03:11
8.
Background
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05:12
9.
除了氣體交換(吸氧排二氧化碳)外, 呼吸系統還有那些功能?
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05:32
10.
Functions of Respiratory Sys.
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07:42
11.
Overview
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10:12
12.
Outline
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10:18
13.
Structure of Respiratory Sys.
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11:07
14.
Function of Nasal Passage
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12:05
15.
Comparison of Airway Structure
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12:38
16.
Airways of a Human Lung
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13:31
17.
Main Airway Branches & Zones
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14:03
18.
Main Airway Branches & Zones
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14:43
19.
Alveoli
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15:30
20.
The Human Lung
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16:23
21.
Blood Supply of Lungs
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18:21
22.
Respiratory Muscles
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20:15
23.
Respiratory Muscles
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22:40
24.
那種呼吸方式比較有效率?
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23:27
25.
那種呼吸方式比較有效率?
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25:35
26.
Pleural layers
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26:57
27.
Cross Section of the Thoracic Cavity
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27:18
28.
Intrapleural Space
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28:49
29.
Pneumothorax
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30:02
30.
Outline
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30:09
31.
Instrument for Measuring Lung Vol.
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32:49
32.
Spirometer, Lung Volumes and Capacities
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36:05
33.
Lung Volumes and Capacities
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37:48
34.
什麼時候正常吐氣結束?
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38:41
35.
什麼時候正常吐氣結束?
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39:03
36.
Functional Residual Capacity
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41:22
37.
Measurement of FRC
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42:15
38.
Measurement of FRC
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44:46
39.
Overview
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44:54
40.
Ventilation (通氣量)
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47:43
41.
Dead Space (死腔)
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50:35
42.
Fowler’s Method:Single-Breath Nitrogen Washout
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51:47
43.
Fowler’s Method:Single-Breath Nitrogen Washout
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55:00
44.
Bohr’s Method:Conservation of Mass
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58:25
45.
Dalton’s Law
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1:01:05
46.
Bohr’s Method (2)
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1:02:01
47.
Alveolar Ventilation
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1:04:11
48.
Alveolar Ventilation
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1:04:47
49.
Uneven Ventilation inUpright Position
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1:05:44
50.
Cause of the Regional Differences of Ventilation
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1:07:38
51.
Closing Volume
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1:11:58
52.
Closing Volume
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1:13:05
53.
Partial Pressures of Gases in Various Parts
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1:13:56
54.
O2 and CO2 Concentrations in Exhaled Gas
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1:15:15
55.
Overview of Po2 and Pco2
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1:18:34
56.
How to measure PAO2?
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1:18:40
57.
Alveolar Gas Equation
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1:19:57
58.
Respiratory Quotient (呼吸商)
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1:23:11
59.
Alveolar Gas Equation
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1:24:08
60.
Reasons to Understand the Alveolar Gas Equation
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1:24:58
61.
Case Study
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1:26:57
62.
改變呼吸方式可改變那種氣體的分壓?
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1:27:29
63.
Hyper-, Hypo-ventilation & Hyperpnea
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1:30:05
64.
跑步後很喘,如何快速回到正常的呼吸速率?
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1:30:52
65.
Why hyperpnea is more efficient?
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1:34:04
66.
Outline
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1:34:11
67.
Overview
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1:34:20
68.
Perfusion (灌流量)
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1:35:18
69.
Shunt (分流)
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1:38:09
70.
Shunt Equation
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1:39:48
71.
Uneven Perfusion in Upright Position
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1:51:04
72.
Zone Model
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1:52:35
73.
Hypoxic Pulmonary Vasoconstriction
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1:54:31
74.
Overview
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1:54:42
75.
Matching of Ventilation & Perfusion
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1:56:02
76.
Mis-matching of Ventilation & Perfusion
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1:56:42
77.
V /Q 受什麼影響?
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1:57:03
78.
Matching of Ventilation & Perfusion
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1:58:35
79.
Distribution of V and Q Within the Lung in the Upright Position
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2:00:02
80.
Distribution of V /Q Ratio
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2:03:04
81.
V /Q 如何影響氣體的分壓?
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2:03:07
82.
Effects of V /Q Ratio on PAo2 & PAco2
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2:04:50
83.
Effects of V /Q Ratio on PAo2 & PAco2
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2:05:38
84.
V /Q v.s. Po2 & Pco2
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2:09:05
85.
V /Q Inequality of Normal Lung in the Upright Position
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2:15:17
86.
Riley’s Three Compartment Model
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2:17:37
87.
Riley’s Three Compartment Model
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2:20:09
88.
Gas Exchange Computer Lab
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2:20:54
89.
Outline
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2:21:04
90.
Key Points
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2:21:10
91.
General Concepts and Terminology
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2:24:04
92.
General Concepts and Terminology
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2:25:30
93.
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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2:30:21
94.
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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2:30:54
95.
Key Points
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2:31:06
96.
Static Mechanical Properties
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2:32:32
97.
Compliance Changes in Different Diseases
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2:33:36
98.
Calculation of Compliance of Lung
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2:35:08
99.
Key Points
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2:35:12
100.
Resistance
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2:36:02
101.
The Airway Resistance
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2:36:50
102.
The Airway Resistance
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2:37:51
103.
The Airway Resistance
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2:39:35
104.
The Airway Resistance
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2:40:28
105.
Calculation of Dynamic Resistance
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2:42:19
106.
Evaluation of Airway Resistance
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2:45:19
107.
Evaluation of Abnormality in Lung Vol.
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2:46:54
108.
Flow-volume Curves
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2:46:55
109.
Evaluation of Abnormality in Lung Vol.
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2:47:00
110.
Flow-volume Curves
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2:48:18
111.
Isovolume Pressure-flow Curves
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2:49:41
112.
Flow-Volume Relationship
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2:50:53
113.
Dynamic Airway Compression
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2:59:52
114.
EPP is Influenced by Lung Elastic Recoil
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3:02:09
115.
Pursed Lip Breathing (噘嘴吐氣)
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3:03:37
116.
Abnormality in Lung Vol.
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3:04:22
117.
Interpretation of Flow-Vol Loop
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3:05:04
118.
Obstructive Lung Vol. Defect
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3:05:36
119.
Chronic Obstructive Pulmonary Disease (慢性阻塞性肺病; COPD)
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3:05:51
120.
Emphysema (肺氣腫)
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3:06:15
121.
Asthma (氣喘)
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3:07:57
122.
吸煙豬肺影片
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3:10:26
123.
Restrictive Lung Vol. Defect
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3:11:27
124.
Examples of Restrictive Lung Dz.
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3:12:05
125.
做那些動作使呼吸效率增加?為什麼?
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3:13:03
126.
做那些動作使呼吸效率增加?為什麼?
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3:14:26
127.
Key Points
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3:14:30
128.
Hysteresis
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3:16:55
129.
Surface Tension
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3:19:01
130.
Law of LaPlace
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3:20:32
131.
Surfactants
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3:21:03
132.
Importance of Lung Surfactant
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3:21:57
133.
Work of Breathing
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3:22:46
134.
Effects of Diseases on PV Curve
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3:24:03
135.
為什麼肺氣腫的病人每次的呼吸都很吃力?
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3:24:06
136.
Effects of Diseases on PV Curve
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3:24:21
137.
為什麼肺氣腫的病人每次的呼吸都很吃力?
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3:24:31
138.
Effects of Diseases on PV Curve
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3:25:36
139.
Key Points
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3:25:48
140.
PL = Pal – Ppl(1)Pw = Ppl – Pbs(2)(1) + (2)Prs = PL + Pw = Pal – Pbsa) Pbs =0 Pw = Ppl = Pes Prs = Palb) Pao = VRaw + Pal When flow=0, Pao = Pal = Prsc) PL = Pal – Ppl = Pao|flow=0 – Pes
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3:26:15
141.
Elastic Recoil of the Chest Wall
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3:28:33
142.
Elastic Recoil of the Chest Wall
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3:31:41
143.
Lung-Chest Wall Couplingin Static Status at Different Lung Volume
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3:31:42
144.
Lung-chest Wall Coupling to Determine FRC
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3:31:43
145.
Lung-Chest Wall Couplingin Static Status at Different Lung Volume
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3:32:12
146.
Lung-chest Wall Coupling to Determine FRC
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3:35:35
147.
Static Elastic Properties of the Lung and Chest Wall
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3:37:18
148.
Static Elastic Properties of the Lung and Chest Wall
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3:38:38
149.
Transmural Pressure Across the Lung Wall in Dynamic Status
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3:40:15
150.
The Mechanics of Quiet Breathing
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3:44:51
151.
P-V Relationships and Schematic Events of Resp. Cycle
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3:49:06
152.
P-V Relationships and Schematic Events of Resp. Cycle
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3:50:38
153.
Outline
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3:50:54
154.
Overview
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3:51:11
155.
Diffusion and Gas Transport
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3:51:53
156.
Alveolo-Capillary Barrier
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3:52:18
157.
Diffusion
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3:52:52
158.
Diffusion Capacity
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3:54:09
159.
Diffusion Capacity
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3:55:37
160.
Physiologic Changes That Alter Diffusion Capacity
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3:56:49
161.
Capillary Transit Time
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3:59:11
162.
Perfusion-limited Gas
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4:00:41
163.
Diffusion-limited Gas
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4:01:18
164.
Diffusion and Perfusion Limitations
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4:03:41
165.
Interpretation of Pulmonary Function Test
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4:06:56
166.
Transport of O2 and CO2
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4:07:03
167.
Oxygen Transport
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4:07:42
168.
Blood Gas Measurement
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4:08:34
169.
Blood Gas Measurement
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4:10:16
170.
O2 Bound to Hb
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4:10:37
171.
O2 Bound to Hb
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4:12:23
172.
What does pulse oximeter measure?O2 dissolved in the blood plasmaO2 bound with hemoglobin
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4:12:52
173.
What does pulse oximeter measure?O2 dissolved in the blood plasmaO2 bound with hemoglobin
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4:13:26
174.
O2 Concentration & Saturation in Anemia
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4:14:01
175.
Cooperative Interactions
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4:16:07
176.
O2 Bound to Hb
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4:18:19
177.
O2 Bound to Hb
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4:20:34
178.
Factors Affecting O2 Bound to Hb
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4:22:11
179.
CO2 Transport
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4:23:03
180.
CO2 Transport
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4:24:31
181.
CO2 Transport
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4:25:05
182.
CO2 Equilibrium Curve
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4:27:30
183.
Assessment of Arterial Hypoxemia
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4:30:47
184.
Example qestions
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4:32:46
185.
Example qestions
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4:34:57
186.
Outline
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4:35:05
187.
Control of Respiration
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4:36:15
188.
Overview
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4:37:30
189.
Receptors
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4:38:41
190.
Receptors
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4:40:18
191.
Receptors
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4:41:26
192.
Central Controller in Brain Stem
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4:41:44
193.
你覺得吸氣比較重要還是呼氣比較重要?
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4:42:30
194.
Central Controller
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4:43:05
195.
Central Controller
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4:44:24
196.
Respiratory Neurons in the Brain Stem
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4:47:48
197.
正常情況下,什麼時候正常呼吸的型態會改變?
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4:48:07
198.
Central Controller
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4:48:52
199.
Central Controller
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4:49:37
200.
Effectors
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4:50:18
201.
Outline
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4:50:25
202.
Overview
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4:50:39
203.
你覺得吸氧氣比較重要還是排二氧化碳比較重要?
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4:50:56
204.
Chemical Control of Resp.
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4:51:49
205.
Central Chemoreceptor
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4:53:28
206.
Peripheral Chemoreceptor
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4:54:38
207.
Silent Hypoxia (Happy Hypoxia)
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4:55:30
208.
Regulation of breathing in response to changes in blood PCO2, PO2, and pH (H+) via negative feedback control
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4:57:16
209.
呼吺調控影片
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4:58:29
210.
Outline
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4:58:33
211.
Acid-base Balance
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5:00:31
212.
Effectiveness of a Buffer System
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5:01:57
213.
Bicarbonate
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5:02:40
214.
The Effect of Bicarbonate on Blood pH
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5:05:05
215.
Davenport Diagram
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5:06:49
216.
Respiratory Disturbances
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5:07:49
217.
Metabolic Disturbances
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5:08:30
218.
Compensatory Responses
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5:11:09
219.
Compensatory Responses
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5:12:07
220.
Outline
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5:12:25
221.
Rest-to-Work Transitions
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5:13:23
222.
Sub-maximal Exercise
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5:13:45
223.
Ventilatory Control During Submaximal Exercise
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5:14:16
224.
High Intensity Exercise
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5:15:11
225.
High Intensity Exercise
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5:16:02
226.
Oxygen Debt
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5:18:02
227.
呼吸系統是運動的限制因子嗎?
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5:18:33
228.
Do the Lungs Limit Exercise Performance?
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5:18:50
229.
Effect of Training on Ventilation
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5:19:25
230.
How to Increase Resp. Function During Exercise?
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5:26:23
231.
How to Increase Resp. Function During Exercise?
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5:29:46
232.
Effect of High Altitude on Resp. Function
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5:31:01
233.
Immediate: Increased in Ventilation
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5:35:00
234.
Days: Decreased Affinity of Hemoglobin for Oxygen
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5:36:44
235.
Days to weeks: Increased Hemoglobin Production
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5:38:32
236.
Respiratory Adaptations to High Altitude
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5:39:51
237.
Overview
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5:51:34
238.
The End