• 00:29 1.
    index 1
  • 00:03 2.
    Slide 1
  • 00:09 3.
    RNA methylation (m6A)
  • 00:23 4.
    Slide 1
  • 00:43 5.
    RNA methylation (m6A)
  • 00:00 6.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:44 7.
    RNA methylation (m6A)
  • 05:47 8.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:29 9.
    m6A motif
  • 02:12 10.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 02:02 11.
    m6A motif
  • 00:19 12.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:00 13.
    m6A motif
  • 00:00 14.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:00 15.
    m6A motif
  • 01:47 16.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:00 17.
    m6A motif
  • 00:00 18.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:00 19.
    m6A motif
  • 00:32 20.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:01 21.
    m6A motif
  • 04:03 22.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 05:02 23.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:09 24.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:55 25.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:33 26.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 01:38 27.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 01:58 28.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 07:43 29.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 00:01 30.
    Summary 1To assess overall levels of m6A modification in gastric cancer……
  • 00:27 31.
    Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
  • 01:04 32.
    Summary 1To assess overall levels of m6A modification in gastric cancer……
  • 01:54 33.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:01 34.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 01:39 35.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:44 36.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 04:55 37.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:44 38.
    S2
  • 00:05 39.
    Slide 14
  • 00:19 40.
    RNA-seq
  • 00:00 41.
    Slide 14
  • 00:00 42.
    S2
  • 00:00 43.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:00 44.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:03 45.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:00 46.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:00 47.
    Fig. 2 ALKBH5 inhibits cell invasion in vitro
  • 00:00 48.
    S2
  • 00:28 49.
    Slide 14
  • 01:02 50.
    RNA-seq
  • 00:03 51.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 06:59 52.
    RNA-seq
  • 01:36 53.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 01:42 54.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 02:25 55.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 00:03 56.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 00:13 57.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 06:59 58.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 00:01 59.
    Slide 20
  • 00:28 60.
    Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
  • 00:20 61.
    Slide 20
  • 02:48 62.
    Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
  • 02:44 63.
    Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
  • 00:01 64.
    Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
  • 06:30 65.
    Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
  • 01:52 66.
    Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
  • 00:16 67.
    Slide 24
  • 01:57 68.
    Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
  • 00:41 69.
    Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
  • 01:26 70.
    Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
  • 02:33 71.
    Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
  • 01:01 72.
    Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
  • 00:03 73.
    Summary 5investigate the potential “reader” in m6A modification of PKMYT1 ……
  • 02:01 74.
    Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
  • 00:34 75.
    Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
  • 00:01 76.
    Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
  • 00:05 77.
    Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
  • 01:16 78.
    Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
  • 01:18 79.
    Slide 34
  • 03:50 80.
    ** after 20220307_逸安 (Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modifcation).pptx
  • Index
  • Notes
  • Comment
  • Fullscreen
20220307 lab meeting_逸安
Duration: 1:43:32, Browse: 145, Last Updated: 2022-03-29
Keypoint
  1. 1.
    Prev Next
    • 00:29 1.
      index 1
    • 00:03 2.
      Slide 1
    • 00:09 3.
      RNA methylation (m6A)
    • 00:23 4.
      Slide 1
    • 00:43 5.
      RNA methylation (m6A)
    • 00:00 6.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:44 7.
      RNA methylation (m6A)
    • 05:47 8.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:29 9.
      m6A motif
    • 02:12 10.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 02:02 11.
      m6A motif
    • 00:19 12.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:00 13.
      m6A motif
    • 00:00 14.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:00 15.
      m6A motif
    • 01:47 16.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:00 17.
      m6A motif
    • 00:00 18.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:00 19.
      m6A motif
    • 00:32 20.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:01 21.
      m6A motif
    • 04:03 22.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 05:02 23.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:09 24.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:55 25.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:33 26.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 01:38 27.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 01:58 28.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 07:43 29.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 00:01 30.
      Summary 1To assess overall levels of m6A modification in gastric cancer……
    • 00:27 31.
      Fig. 1 MeRIP-seq reveals correlation between m6A and cell adhesion, and ALKBH5 is associated with GC prognosis
    • 01:04 32.
      Summary 1To assess overall levels of m6A modification in gastric cancer……
    • 01:54 33.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:01 34.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 01:39 35.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:44 36.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 04:55 37.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:44 38.
      S2
    • 00:05 39.
      Slide 14
    • 00:19 40.
      RNA-seq
    • 00:00 41.
      Slide 14
    • 00:00 42.
      S2
    • 00:00 43.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:00 44.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:03 45.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:00 46.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:00 47.
      Fig. 2 ALKBH5 inhibits cell invasion in vitro
    • 00:00 48.
      S2
    • 00:28 49.
      Slide 14
    • 01:02 50.
      RNA-seq
    • 00:03 51.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 06:59 52.
      RNA-seq
    • 01:36 53.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 01:42 54.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 02:25 55.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 00:03 56.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 00:13 57.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 06:59 58.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 00:01 59.
      Slide 20
    • 00:28 60.
      Fig. 3 PKMYT1 was identified as a downstream target of ALKBH5
    • 00:20 61.
      Slide 20
    • 02:48 62.
      Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
    • 02:44 63.
      Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
    • 00:01 64.
      Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
    • 06:30 65.
      Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
    • 01:52 66.
      Fig. 4 ALKBH5 regulates PKMYT1 via its m6A-dependent manner
    • 00:16 67.
      Slide 24
    • 01:57 68.
      Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
    • 00:41 69.
      Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
    • 01:26 70.
      Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
    • 02:33 71.
      Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
    • 01:01 72.
      Fig. 5 ALKBH5 and IGF2BP3 together regulates the expression of PKMYT1 via its m6A modification
    • 00:03 73.
      Summary 5investigate the potential “reader” in m6A modification of PKMYT1 ……
    • 02:01 74.
      Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
    • 00:34 75.
      Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
    • 00:01 76.
      Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
    • 00:05 77.
      Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
    • 01:16 78.
      Fig. 6 ALKBH5-PKMYT1-IGF2BP3 axis inhibits invasion and migration in vivo
    • 01:18 79.
      Slide 34
    • 03:50 80.
      ** after 20220307_逸安 (Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modifcation).pptx
    Location
    1. Media Center
    2. ...
    3. 2022
    Folder name
    2022
    Author
    柯怡君
    Branch
    賴亮全教授
    Created
    2022-03-07 11:05:58
    Last Updated
    2022-03-29 09:58:21
    Browse
    145
    Duration
    1:43:32

    臺北市仁愛路一段1號10樓1009室

    R1009 10F No1 Sec1 Ren-Ai Rd, Taipei 100233, Taiwan.

    E-mail: llai@ntu.edu.tw

    Tel: 886-2-2312-3456 # 288241

    Lab: 886-2-2393-8235