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00:00
1.
index 1
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00:21
2.
Metabolic heterogeneity in lung tumors
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01:08
3.
LncRNA ADPGK-AS1 was upregulated in TAMs
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04:10
4.
LncRNA ADPGK-AS1 was upregulated in TAMs in association with mitochondria
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04:12
5.
LncRNA ADPGK-AS1 was upregulated in TAMs
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05:40
6.
LncRNA ADPGK-AS1 was upregulated in TAMs in association with mitochondria
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11:50
7.
MRPL35 was abundant in M2-like TAMs
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18:52
8.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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23:32
9.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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25:12
10.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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25:13
11.
ADPGK-AS1 overexpression increased levels of TCA cycle metabolites
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25:13
12.
ADPGK-AS1 overexpression decreased ROS levels
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25:14
13.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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25:14
14.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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25:15
15.
ADPGK-AS1 overexpression in macrophages induced a tumor-promoting M2-like phenotype
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25:15
16.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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25:16
17.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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25:16
18.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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25:16
19.
ADPGK-AS1 influenced human lung tumor progression ex vivo
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25:17
20.
CircZFR modulated MYO1B splicing
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25:17
21.
Slide 19
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25:17
22.
Thank you for listening
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25:18
23.
RNA therapy
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25:18
24.
Oxygen consumption rate (OCR)
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28:58
25.
RNA therapy
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28:59
26.
Thank you for listening
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28:59
27.
Slide 19
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28:59
28.
CircZFR modulated MYO1B splicing
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29:00
29.
ADPGK-AS1 influenced human lung tumor progression ex vivo
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29:00
30.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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29:01
31.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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29:01
32.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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29:02
33.
ADPGK-AS1 overexpression in macrophages induced a tumor-promoting M2-like phenotype
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29:03
34.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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29:03
35.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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29:04
36.
ADPGK-AS1 overexpression decreased ROS levels
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29:05
37.
ADPGK-AS1 overexpression increased levels of TCA cycle metabolites
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29:05
38.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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29:06
39.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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29:08
40.
ADPGK-AS1 overexpression altered the regulation of mitochondrial metabolism
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30:20
41.
ADPGK-AS1 overexpression increased levels of TCA cycle metabolites
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36:55
42.
ADPGK-AS1 overexpression decreased ROS levels
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38:57
43.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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39:00
44.
ADPGK-AS1 overexpression decreased ROS levels
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39:07
45.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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41:32
46.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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41:37
47.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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41:38
48.
Macrophages upregulated ADPGK-AS1 and adapted their metabolic signaling pathways after crosstalk with tumor cells
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45:33
49.
ADPGK-AS1 overexpression in macrophages induced a tumor-promoting M2-like phenotype
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49:03
50.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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50:11
51.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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50:13
52.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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50:14
53.
ADPGK-AS1 overexpression in macrophages induced a tumor-promoting M2-like phenotype
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50:33
54.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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50:33
55.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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50:34
56.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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50:35
57.
ADPGK-AS1 overexpression in macrophages induced a tumor-promoting M2-like phenotype
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51:09
58.
ADPGK-AS1 knockdown in macrophages induced M1-like phenotype
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51:10
59.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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57:37
60.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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57:41
61.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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58:29
62.
ADPGK-AS1 knockdown inhibited tumor growth in vivo
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1:01:25
63.
ADPGK-AS1 influenced human lung tumor progression ex vivo
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1:04:03
64.
CircZFR modulated MYO1B splicing
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1:04:16
65.
Slide 19
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1:06:32
66.
Thank you for listening
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1:06:42
67.
** after 20240219 lab meeting_俐妤.pptx