20231225 lab meeting_楷軒 | 賴亮全實驗室

索引

00:00 1.
index 1
00:21 2.
Slide 2
01:05 3.
Slide 3
01:57 4.
CircRNA
07:41 5.
CircRNA and diseases
08:03 6.
gastric cancer
08:59 7.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
15:46 8.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
16:49 9.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
16:53 10.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
33:43 11.
CircMTHFD2L is more stable than linear, and located in cytoplasm
40:40 12.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
51:31 13.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
52:40 14.
Low CM-248aa promotes overall survival in GC patients
53:01 15.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
53:02 16.
Low CM-248aa promotes overall survival in GC patients
55:04 17.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
57:44 18.
Low CM-248aa promotes overall survival in GC patients
57:44 19.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
57:45 20.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
58:02 21.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
58:03 22.
Low CM-248aa promotes overall survival in GC patients
58:03 23.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
59:37 24.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
59:44 25.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
1:04:29 26.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
1:08:12 27.
GC progression is repressed by CM-248aa
1:10:06 28.
GC progression is repressed by CM-248aa
1:11:04 29.
GC progression is repressed by CM-248aa
1:13:52 30.
GC progression is repressed by CM-248aa
1:14:16 31.
GC progression is repressed by CM-248aa
1:14:18 32.
SET might potentially interact with CM-248aa
1:14:19 33.
GC progression is repressed by CM-248aa
1:14:29 34.
GC progression is repressed by CM-248aa
1:15:24 35.
GC progression is repressed by CM-248aa
1:15:39 36.
SET might potentially interact with CM-248aa
1:18:29 37.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:25:47 38.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:25:50 39.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:26:30 40.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:37:54 41.
CM-248aa represses GC growth in animal model
1:38:17 42.
CM-248aa inhibits p-AKT, p-ERK,p-P65 positive signal in IHC staining
1:38:43 43.
CM-248aa represses GC metastasis to lung in animal model
1:40:07 44.
Conclusion
1:41:01 45.
Pros
1:41:56 46.
Slide 28
1:42:00 47.
Pros
1:42:00 48.
Conclusion

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討論

00:00 1.
index 1
00:21 2.
Slide 2
01:05 3.
Slide 3
01:57 4.
CircRNA
07:41 5.
CircRNA and diseases
08:03 6.
gastric cancer
08:59 7.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
15:46 8.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
16:49 9.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
16:53 10.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
33:43 11.
CircMTHFD2L is more stable than linear, and located in cytoplasm
40:40 12.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
51:31 13.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
52:40 14.
Low CM-248aa promotes overall survival in GC patients
53:01 15.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
53:02 16.
Low CM-248aa promotes overall survival in GC patients
55:04 17.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
57:44 18.
Low CM-248aa promotes overall survival in GC patients
57:44 19.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
57:45 20.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
58:02 21.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
58:03 22.
Low CM-248aa promotes overall survival in GC patients
58:03 23.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
59:37 24.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
59:44 25.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
1:04:29 26.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
1:08:12 27.
GC progression is repressed by CM-248aa
1:10:06 28.
GC progression is repressed by CM-248aa
1:11:04 29.
GC progression is repressed by CM-248aa
1:13:52 30.
GC progression is repressed by CM-248aa
1:14:16 31.
GC progression is repressed by CM-248aa
1:14:18 32.
SET might potentially interact with CM-248aa
1:14:19 33.
GC progression is repressed by CM-248aa
1:14:29 34.
GC progression is repressed by CM-248aa
1:15:24 35.
GC progression is repressed by CM-248aa
1:15:39 36.
SET might potentially interact with CM-248aa
1:18:29 37.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:25:47 38.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:25:50 39.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:26:30 40.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:37:54 41.
CM-248aa represses GC growth in animal model
1:38:17 42.
CM-248aa inhibits p-AKT, p-ERK,p-P65 positive signal in IHC staining
1:38:43 43.
CM-248aa represses GC metastasis to lung in animal model
1:40:07 44.
Conclusion
1:41:01 45.
Pros
1:41:56 46.
Slide 28
1:42:00 47.
Pros
1:42:00 48.
Conclusion

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20231225 lab meeting_楷軒

長度: 1:42:16, 瀏覽: 92, 最近修訂: 2023-12-25

00:00 1.
index 1
00:21 2.
Slide 2
01:05 3.
Slide 3
01:57 4.
CircRNA
07:41 5.
CircRNA and diseases
08:03 6.
gastric cancer
08:59 7.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
15:46 8.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
16:49 9.
hsa_circ_0069982 is selected from 12 DEcircRNAs in GC
16:53 10.
CircMTHFD2L is a downregulated circRNA with coding potential in GC
33:43 11.
CircMTHFD2L is more stable than linear, and located in cytoplasm
40:40 12.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
51:31 13.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
52:40 14.
Low CM-248aa promotes overall survival in GC patients
53:01 15.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
53:02 16.
Low CM-248aa promotes overall survival in GC patients
55:04 17.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
57:44 18.
Low CM-248aa promotes overall survival in GC patients
57:44 19.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
57:45 20.
circMTHFD2L binds to polysomes and be translated but not ATG mutant
58:02 21.
CM-248aa decrease expression in GC. and CM-248aa is verified in both endogenous or exogenous
58:03 22.
Low CM-248aa promotes overall survival in GC patients
58:03 23.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
59:37 24.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
59:44 25.
The subcellular localization of endogenous CM-248aawas distributed mainly in the nucleus by NLS
1:04:29 26.
CM-248aa protein or mRNA expression is regulated by circMTHFD2L
1:08:12 27.
GC progression is repressed by CM-248aa
1:10:06 28.
GC progression is repressed by CM-248aa
1:11:04 29.
GC progression is repressed by CM-248aa
1:13:52 30.
GC progression is repressed by CM-248aa
1:14:16 31.
GC progression is repressed by CM-248aa
1:14:18 32.
SET might potentially interact with CM-248aa
1:14:19 33.
GC progression is repressed by CM-248aa
1:14:29 34.
GC progression is repressed by CM-248aa
1:15:24 35.
GC progression is repressed by CM-248aa
1:15:39 36.
SET might potentially interact with CM-248aa
1:18:29 37.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:25:47 38.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:25:50 39.
CM-248aa inhibits phosphorylation of AKT, ERK, P65 by SET
1:26:30 40.
SET interacts with CM-248aa by salt bridge, inhibiting PP2Ac expression
1:37:54 41.
CM-248aa represses GC growth in animal model
1:38:17 42.
CM-248aa inhibits p-AKT, p-ERK,p-P65 positive signal in IHC staining
1:38:43 43.
CM-248aa represses GC metastasis to lung in animal model
1:40:07 44.
Conclusion
1:41:01 45.
Pros
1:41:56 46.
Slide 28
1:42:00 47.
Pros
1:42:00 48.
Conclusion

位置

資料夾名稱

2023

發表人

周楷軒

單位

賴亮全教授

建立

2023-12-25 11:56:23

最近修訂

2023-12-25 13:56:16

長度

1:42:16