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00:00
1.
Nomenclature of Cytogenetics
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02:57
2.
Example of AML
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04:36
3.
Question
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06:23
4.
3-D Structure of Genomes: 3C
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07:47
5.
3-D Structure of Genomes: 4C/5C
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09:11
6.
3-D Structure of Genomes: HiC
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10:58
7.
3-D Structure of Genomes: ChIA-PET
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12:40
8.
Cell Immortalization
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16:12
9.
Question
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17:13
10.
Ways to Generate Site Specific Double-Strand DNA Breaks
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18:31
11.
TALEN Technology
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23:39
12.
CRISPR Genome Engineering
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31:21
13.
Websites for Designing sgRNA
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31:28
14.
CRISPR Genome Engineering
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33:47
15.
CRISPR application
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35:21
16.
Transposons
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37:15
17.
PiggyBac Transposon System
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38:38
18.
RNA-guided DNA transposition
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40:09
19.
RNA-Guided Platform for Sequence-Specific Control of Gene
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43:25
20.
Type VI CRISPR
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43:37
21.
Knockout Mice vs Transgenics
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45:26
22.
Making Knockout / Transgenic Mice
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47:02
23.
Schematic and Time Line
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47:37
24.
DNA Incorporation & Identification of Transgenic Cells
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48:32
25.
Positive and Negative Selection
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51:19
26.
Schematic and Time Line
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52:05
27.
Schematic and Time Line
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54:41
28.
Comparison of Time line
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57:14
29.
Conditional Knock-out
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1:00:49
30.
Tissue-Specific Knock-out
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1:05:04
31.
Conditional Knock-out(Time Specific)
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1:07:27
32.
Mouse Strain Nomenclature
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1:09:51
33.
Transgenic Mouse Strain Nomenclature
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1:10:40
34.
A Laboratory Code
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1:11:27
35.
Congenic Strain
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1:12:21
36.
Knockout Mouse Strain Nomenclature
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1:14:20
37.
Nude mice
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1:18:48
38.
Severe Combined Immunodeficiency (SCID) Mice
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1:20:16
39.
NSG Mouse
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1:23:15
40.
NSG-SGM3 Mouse
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1:24:53
41.
Humanize PDX mouse (擬人鼠)