• 00:00 1.
    Applications
  • 00:03 2.
    Liver/muscle cell exampleSame genes, so same % in genomeVery different cellular protein abundance
  • 00:53 3.
    Epigenetics
  • 01:42 4.
    Epigenetic Mechanisms
  • 02:15 5.
    DNA Methylation1
  • 04:57 6.
    DNA Methyltransferases
  • 06:39 7.
    Ten-Eleven Translocation Protein Family
  • 09:16 8.
    Eight Nucleotide Base
  • 10:06 9.
    DNA Methylation2
  • 14:06 10.
    EMBOSS Cpgplot
  • 14:33 11.
    Correlation of Methylation Profile With Expression Level
  • 14:52 12.
    Chromatin Regions
  • 16:40 13.
    Mechanisms of Gene Silencing
  • 19:42 14.
    Mechanisms of Gene Silencing
  • 20:49 15.
    An Example of Silencing Precedes DNA Methylation
  • 22:49 16.
    Functions of DNA Methylation
  • 28:54 17.
    DNA Methylation in Carcinogenesis
  • 29:29 18.
    Plots for Expressing DNA Methylation Status
  • 30:41 19.
    Methodologies For Detection of DNA Methylation
  • 31:06 20.
    Methylation-Sensitive Restriction Enzymes
  • 35:52 21.
    5-hmC Detection Method
  • 37:23 22.
    5-hmC Detection Method
  • 38:00 23.
    Methodologies For Detection of DNA Methylation
  • 38:14 24.
    Bisulfite Conversion
  • 42:51 25.
    Methylation-Specific PCR (MSP)
  • 43:59 26.
    Bisulfite Sequencing
  • 47:09 27.
    MethPrimer
  • 48:14 28.
    Analyses of Epigenetic Modifications Using NGS
  • 48:32 29.
    QUMA
  • 48:46 30.
    QUMA: Feature Overview
  • 49:11 31.
    Illumina Infinium Methylation Assay
  • 50:07 32.
    Illumina Infinium Methylation Assay
  • 52:03 33.
    Illumina Infinium Methylation Assay
  • 52:54 34.
    Illumina Infinium Methylation Assay
  • 54:20 35.
    Pyrosequencing for DNA Methylation Analysis
  • 54:55 36.
    EpiTYPER Methylation Assay (Sequenom)
  • 55:28 37.
    EpiTYPER Methylation Assay (Sequenom)
  • 55:41 38.
    Methylation Analysis Biochemistry
  • 57:58 39.
    Cleavage Reaction
  • 58:04 40.
    Quantitation of Methylation Ratios
  • 58:39 41.
    Methodologies for Detection of DNA Methylation
  • 58:52 42.
    Affinity Purification
  • 59:37 43.
    Detecting Modified DNA Bases During SMRT Sequencing
  • 1:03:51 44.
    Single-cell Methylomes
  • 1:04:21 45.
    Concurrent Analysis of Genetics and Epigenetics
  • 1:08:32 46.
    RNA Methylation
  • 1:10:12 47.
    RNA methylation
  • 1:11:54 48.
    Functions of m6A Methylation
  • 1:12:27 49.
    m6A modification on noncoding RNAs
  • 1:13:38 50.
    MeRIP-seq: Methylated RNA Immunopreciptation Sequencing
  • Index
  • Notes
  • Comment
  • Fullscreen
Epigenetics_nucleic acid methylation (0511)
Duration: 1:15:07, Browse: 422, Last Updated: 2021-05-12
    • 00:00 1.
      Applications
    • 00:03 2.
      Liver/muscle cell exampleSame genes, so same % in genomeVery different cellular protein abundance
    • 00:53 3.
      Epigenetics
    • 01:42 4.
      Epigenetic Mechanisms
    • 02:15 5.
      DNA Methylation1
    • 04:57 6.
      DNA Methyltransferases
    • 06:39 7.
      Ten-Eleven Translocation Protein Family
    • 09:16 8.
      Eight Nucleotide Base
    • 10:06 9.
      DNA Methylation2
    • 14:06 10.
      EMBOSS Cpgplot
    • 14:33 11.
      Correlation of Methylation Profile With Expression Level
    • 14:52 12.
      Chromatin Regions
    • 16:40 13.
      Mechanisms of Gene Silencing
    • 19:42 14.
      Mechanisms of Gene Silencing
    • 20:49 15.
      An Example of Silencing Precedes DNA Methylation
    • 22:49 16.
      Functions of DNA Methylation
    • 28:54 17.
      DNA Methylation in Carcinogenesis
    • 29:29 18.
      Plots for Expressing DNA Methylation Status
    • 30:41 19.
      Methodologies For Detection of DNA Methylation
    • 31:06 20.
      Methylation-Sensitive Restriction Enzymes
    • 35:52 21.
      5-hmC Detection Method
    • 37:23 22.
      5-hmC Detection Method
    • 38:00 23.
      Methodologies For Detection of DNA Methylation
    • 38:14 24.
      Bisulfite Conversion
    • 42:51 25.
      Methylation-Specific PCR (MSP)
    • 43:59 26.
      Bisulfite Sequencing
    • 47:09 27.
      MethPrimer
    • 48:14 28.
      Analyses of Epigenetic Modifications Using NGS
    • 48:32 29.
      QUMA
    • 48:46 30.
      QUMA: Feature Overview
    • 49:11 31.
      Illumina Infinium Methylation Assay
    • 50:07 32.
      Illumina Infinium Methylation Assay
    • 52:03 33.
      Illumina Infinium Methylation Assay
    • 52:54 34.
      Illumina Infinium Methylation Assay
    • 54:20 35.
      Pyrosequencing for DNA Methylation Analysis
    • 54:55 36.
      EpiTYPER Methylation Assay (Sequenom)
    • 55:28 37.
      EpiTYPER Methylation Assay (Sequenom)
    • 55:41 38.
      Methylation Analysis Biochemistry
    • 57:58 39.
      Cleavage Reaction
    • 58:04 40.
      Quantitation of Methylation Ratios
    • 58:39 41.
      Methodologies for Detection of DNA Methylation
    • 58:52 42.
      Affinity Purification
    • 59:37 43.
      Detecting Modified DNA Bases During SMRT Sequencing
    • 1:03:51 44.
      Single-cell Methylomes
    • 1:04:21 45.
      Concurrent Analysis of Genetics and Epigenetics
    • 1:08:32 46.
      RNA Methylation
    • 1:10:12 47.
      RNA methylation
    • 1:11:54 48.
      Functions of m6A Methylation
    • 1:12:27 49.
      m6A modification on noncoding RNAs
    • 1:13:38 50.
      MeRIP-seq: Methylated RNA Immunopreciptation Sequencing
    Location
    Folder name
    2021
    Author
    賴亮全
    Branch
    賴亮全教授
    Created
    2021-05-12 16:33:48
    Last Updated
    2021-05-12 17:16:50
    Duration
    1:15:07